TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.0300nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.0300nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.0600nMAssay Description:Agonist activity at human PPARdelta receptor by cell based transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand Info
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.100nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.180nMAssay Description:Agonist activity at human PPARbeta expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.200nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand Info
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.300nMAssay Description:Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as recepto...More data for this Ligand-Target Pair
Ligand Info
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.400nMAssay Description:Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as recepto...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at pSG5-Gal4-tagged human PPAR-beta/delta ligand binding domain expressed in COS1 cells assessed as receptor activation incubated fo...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at GAL4-fused human PPARdelta DNA binding domain expressed in HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.5nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand Info
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at PPARdelta (unknown origin)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.580nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.700nMAssay Description:Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as recepto...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.700nMAssay Description:Transactivation of GAL4-fused human PPARdelta expressed in African green monkey CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.700nMAssay Description:Transactivation of human PPARdelta expressed in monkey CV-1 cells coexpressing TK-PPRE-Luc after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.720nMAssay Description:Agonist activity at PPARdelta receptor expressed in HEK293 cells cotransfected with GAL4 by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.720nMAssay Description:Transactivation of Gal4-fused human PPARdelta expressed in HEK293 cells after 16 to 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.800nMAssay Description:Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as recepto...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.800nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand Info
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.910nMAssay Description:Effect on PPARdelta transactivation activity in HEK293 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 0.950nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPAR delta by cell based reporter assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: <1nMAssay Description:After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at PPAR delta (unknown origin) transfected in HEK293 cells after 24 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPAR-delta expressed in african green monkey CV-1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human PPARdelta expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Transactivation of human PPARdelta in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Transactivation activity at human PPARdelta expressed in african green monkey CV1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Effective concentration against PPAR delta receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Activity at PPARbeta/delta by luciferase reporter gene transactivation assay in COS7 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human Gal4-PPARdelta expressed in CV1 cells by transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...More data for this Ligand-Target Pair
Ligand InfoPurchase
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at PPARdelta (unknown origin)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Modulator activity at GAL4-fused human PPARdelta LBD (128 to residue at C-terminus) transfected in African green monkey CV1 cells assessed as recepto...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at PPARdelta (unknown origin)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: <1nMAssay Description:After 24 h treatment with the medicament, the cells were lysed with a lysis solution (Cell Culture Lysis buffer, Promega) and centrifuged, and the su...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:The confluent HEK293 cells were co-transfected with DNA construct containing PPARdelta-Gal4 chimeric receptor and Gal4-luciferase reporter. The lucif...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:The ligand binding domain for PPAR was fused to the yeast transcription factor GAL4 DNA binding domain. CV-1 cells were transiently transfected with ...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Maximum transcriptional activation of human PPAR delta receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Maximum transcriptional activation of human PPAR delta receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Transactivation activity at human PPARdelta expressed in african green monkey CV1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at human PPAR delta by cell based reporter assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Transactivation activity at human PPARdelta expressed in african green monkey CV1 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at human PPARdelta expressed in HepG2 cells cotransfected with PPRE3-TK-luc assessed as beta-galactosidase activity after 20 to 22 h...More data for this Ligand-Target Pair
