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TargetBromodomain-containing protein 2 [364-436](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092323(CHEMBL3581656 | US9675697, Cpd. No. 21)
Affinity DataKi: <10nM ΔG°: <-45.7kJ/mole IC50:  93nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [364-436](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179460(US9675697, Cpd. No. 17)
Affinity DataKi: <10nM ΔG°: <-45.7kJ/mole IC50:  142nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179460(US9675697, Cpd. No. 17)
Affinity DataKi:  16nM ΔG°:  -44.5kJ/mole IC50:  197nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [364-436](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179457(US9675697, Cpd. No. 3)
Affinity DataKi:  35nM ΔG°:  -42.6kJ/mole IC50:  255nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092323(CHEMBL3581656 | US9675697, Cpd. No. 21)
Affinity DataKi:  38nM ΔG°:  -42.4kJ/mole IC50:  310nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [364-436](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092318(CHEMBL3581657 | US9675697, Cpd. No. 2)
Affinity DataKi:  42.3nM ΔG°:  -42.1kJ/mole IC50:  286nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [364-436](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179458(US9675697, Cpd. No. 4)
Affinity DataKi:  57nM ΔG°:  -41.3kJ/mole IC50:  349nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179457(US9675697, Cpd. No. 3)
Affinity DataKi:  83nM ΔG°:  -40.4kJ/mole IC50:  514nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092318(CHEMBL3581657 | US9675697, Cpd. No. 2)
Affinity DataKi:  114nM ΔG°:  -39.6kJ/mole IC50:  608nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179458(US9675697, Cpd. No. 4)
Affinity DataKi:  232nM ΔG°:  -37.9kJ/mole IC50:  873nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [364-436](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092339(CHEMBL3581648 | US9675697, RX-7)
Affinity DataKi:  366nM ΔG°:  -36.7kJ/mole IC50:  1.35E+3nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179476(US9675697, Cpd. No. 34)
Affinity DataKi:  775nM ΔG°:  -34.9kJ/mole IC50:  3.67E+3nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50092339(CHEMBL3581648 | US9675697, RX-7)
Affinity DataKi:  850nM ΔG°:  -34.6kJ/mole IC50:  2.90E+3nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [364-436](Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM179476(US9675697, Cpd. No. 34)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.8kJ/mole IC50:  3.20E+3nMpH: 7.5 T: 2°CAssay Description:The FAM labeled fluorescent probe (BRD-1F) was synthesized based on a known small-molecule BET bromodomain inhibitor. Kd values of BRD-1F to these th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent