Compile Data Set for Download or QSAR
maximum 50k data
Found 260 Enz. Inhib. hit(s) with all data for entry = 10010
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651298(6-[3-fluoro-4-(4-methylpyridin-3-yl)phenyl]-4,5-di...)
Affinity DataIC50:  28nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651262(6-[3-fluoro-4-(pyridin-4-yl)phenyl]-4,5-dihydropyr...)
Affinity DataIC50:  31nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651342(6-(2'-methoxy-2-methyl[1,1'-biphenyl]-4-yl)-4,5-di...)
Affinity DataIC50:  32nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651262(6-[3-fluoro-4-(pyridin-4-yl)phenyl]-4,5-dihydropyr...)
Affinity DataIC50:  33nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651285(6-(2,2',3'-trifluoro[1,1'-biphenyl]-4-yl)-4,5-dihy...)
Affinity DataIC50:  34nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651303(6-[3-fluoro-4-(2-fluoropyridin-3-yl)phenyl]-4,5-di...)
Affinity DataIC50:  35nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651241(6-(3'-Amino-4'-chloro-2-fluorobiphenyl-4-yl)-4,5-d...)
Affinity DataIC50:  35nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651239(6-[4-(3,6-Dihydro-2H-pyran-4-yl)-3-methylphenyl]-4...)
Affinity DataIC50:  35nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651345(2'-methyl-4'-(6-oxo-1,4,5,6-tetrahydropyridazin-3-...)
Affinity DataIC50:  36nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651264(6-[3-fluoro-4-(2-methoxypyridin-4-yl)phenyl]-4,5-d...)
Affinity DataIC50:  36nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651278(2'-fluoro-4'-(6-oxo-1,4,5,6-tetrahydropyridazin-3-...)
Affinity DataIC50:  37nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651324(6-[3-methyl-4-(6-methylpyridin-3-yl)phenyl]-4,5-di...)
Affinity DataIC50:  38nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651303(6-[3-fluoro-4-(2-fluoropyridin-3-yl)phenyl]-4,5-di...)
Affinity DataIC50:  39nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651237(6-[3-Methyl-4-(pyridin-4-yl)phenyl]-4,5-dihydropyr...)
Affinity DataIC50:  39nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651304(6-[3-fluoro-4-(3-methylpyridin-4-yl)phenyl]-4,5-di...)
Affinity DataIC50:  39nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651281(6-(2-fluoro-3'-hydroxy[1,1'-biphenyl]-4-yl)-4,5-di...)
Affinity DataIC50:  41nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651342(6-(2'-methoxy-2-methyl[1,1'-biphenyl]-4-yl)-4,5-di...)
Affinity DataIC50:  42nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651291(6-(2,2'-difluoro[1,1'-biphenyl]-4-yl)-4,5-dihydrop...)
Affinity DataIC50:  47nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651346(6-(4'-amino-2-methyl[1,1'-biphenyl]-4-yl)-4,5-dihy...)
Affinity DataIC50:  47nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651321(6-[4-(2-aminopyridin-4-yl)-3-methylphenyl]-4,5-dih...)
Affinity DataIC50:  47nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651293(6-(2-fluoro-2'-methoxy[1,1'-biphenyl]-4-yl)-4,5-di...)
Affinity DataIC50:  47nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651240(6-(2,4'-Difluorobiphenyl-4-yl)-4,5-dihydropyridazi...)
Affinity DataIC50:  49nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651324(6-[3-methyl-4-(6-methylpyridin-3-yl)phenyl]-4,5-di...)
Affinity DataIC50:  49nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651266(6-[3-fluoro-4-(6-methylpyridin-3-yl)phenyl]-4,5-di...)
Affinity DataIC50:  50nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651253(6-[4-(6,6-Difluoro-3-azabicyclo[3.1.1]hept-3-yl)-3...)
Affinity DataIC50:  50nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651301(6-[3-fluoro-4-(2-methoxypyridin-3-yl)phenyl]-4,5-d...)
Affinity DataIC50:  50nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651287(6-(2,2',4'-trifluoro[1,1'-biphenyl]-4-yl)-4,5-dihy...)
Affinity DataIC50:  50nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651304(6-[3-fluoro-4-(3-methylpyridin-4-yl)phenyl]-4,5-di...)
Affinity DataIC50:  52nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651345(2'-methyl-4'-(6-oxo-1,4,5,6-tetrahydropyridazin-3-...)
Affinity DataIC50:  53nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651298(6-[3-fluoro-4-(4-methylpyridin-3-yl)phenyl]-4,5-di...)
Affinity DataIC50:  56nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651266(6-[3-fluoro-4-(6-methylpyridin-3-yl)phenyl]-4,5-di...)
Affinity DataIC50:  57nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651322(6-[4-(2-aminopyrimidin-5-yl)-3-methylphenyl]-4,5-d...)
Affinity DataIC50:  57nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651301(6-[3-fluoro-4-(2-methoxypyridin-3-yl)phenyl]-4,5-d...)
Affinity DataIC50:  57nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651331(2'-methyl-4'-(6-oxo-1,4,5,6-tetrahydropyridazin-3-...)
Affinity DataIC50:  58nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651331(2'-methyl-4'-(6-oxo-1,4,5,6-tetrahydropyridazin-3-...)
Affinity DataIC50:  59nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651357(6-[4-(Morpholin-4-yl)-3-(trifluoromethyl)phenyl]-4...)
Affinity DataIC50:  59nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651355(6-[3,5-dichloro-4-(morpholin-4-yl)phenyl]-4,5-dihy...)
Affinity DataIC50:  59nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651289(6-(2,5'-difluoro-2'-methyl[1,1'-biphenyl]-4-yl)-4,...)
Affinity DataIC50:  60nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651323(6-[3-methyl-4-(2-methylpyrimidin-5-yl)phenyl]-4,5-...)
Affinity DataIC50:  61nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651278(2'-fluoro-4'-(6-oxo-1,4,5,6-tetrahydropyridazin-3-...)
Affinity DataIC50:  61nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651287(6-(2,2',4'-trifluoro[1,1'-biphenyl]-4-yl)-4,5-dihy...)
Affinity DataIC50:  62nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651244(6-[4-(4,4-Difluoropiperidin-1-yl)-3,5-difluorophen...)
Affinity DataIC50:  62nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651288(6-(2-fluoro-2',4'-dimethyl[1,1'-biphenyl]-4-yl)-4,...)
Affinity DataIC50:  62nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651281(6-(2-fluoro-3'-hydroxy[1,1'-biphenyl]-4-yl)-4,5-di...)
Affinity DataIC50:  63nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651264(6-[3-fluoro-4-(2-methoxypyridin-4-yl)phenyl]-4,5-d...)
Affinity DataIC50:  64nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651284(6-(2'-ethoxy-2-fluoro[1,1'-biphenyl]-4-yl)-4,5-dih...)
Affinity DataIC50:  65nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651234(6-[3-Methyl-4-(pyridin-3-yl)phenyl]-4,5-dihydropyr...)
Affinity DataIC50:  65nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651321(6-[4-(2-aminopyridin-4-yl)-3-methylphenyl]-4,5-dih...)
Affinity DataIC50:  65nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651250(6-[4-(Ethylamino)-3-(trifluoromethyl)phenyl]-4,5-d...)
Affinity DataIC50:  66nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM651265(6-[3-fluoro-4-(2-methylpyridin-3-yl)phenyl]-4,5-di...)
Affinity DataIC50:  66nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand Info
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