Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 6266
TargetHistone deacetylase 8(Homo sapiens (Human))
North Dakota State University

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataKd:  490nMAssay Description:To determine the dissociation rate of the inhibitor, 1 µM HDAC8 and 20 µM inhibitor (syringe I) were mixed with 100 µM c-SAHA (syringe...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
North Dakota State University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataKd:  1.20E+3nMpH: 7.5Assay Description:A fixed concentration of 1.5 µM was titrated with an increasing concentration of the respective inhibitor in protein storage buffer containing 5...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
North Dakota State University

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataKd:  6.80E+3nMAssay Description:To determine the dissociation rate of the inhibitor, 1 µM HDAC8 and 20 µM inhibitor (syringe I) were mixed with 100 µM c-SAHA (syringe...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
North Dakota State University

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataKd:  390nMpH: 7.5Assay Description:A fixed concentration of 1.5 µM was titrated with an increasing concentration of the respective inhibitor in protein storage buffer containing 5...More data for this Ligand-Target Pair