Compile Data Set for Download or QSAR
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Found 21 Enz. Inhib. hit(s) with all data for entry = 50019751
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50:  7nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50074922((+-)-2-fluoro-alpha-methyl-4-biphenylacetic acid |...)
Affinity DataIC50:  10nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50074922((+-)-2-fluoro-alpha-methyl-4-biphenylacetic acid |...)
Affinity DataIC50:  10nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataIC50:  20nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207445(CHEMBL254377 | N-(2-(1-(4-bromobenzyl)-5-methoxy-2...)
Affinity DataIC50:  50nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207449(2-(1-(4-bromobenzyl)-5-methoxy-2-methyl-1H-indol-3...)
Affinity DataIC50:  50nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM22967(2-phenylethyl 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50:  50nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM22966(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  60nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataIC50:  70nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataIC50:  77nMAssay Description:Inhibition of mouse wild type COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207447((Z)-2-(2-(2,6-dichlorophenylamino)benzyloxyimino)p...)
Affinity DataIC50:  100nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207448(2-(2',6'-diethoxy-2-fluoro-biphenyl4-yl)-propionic...)
Affinity DataIC50:  100nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207447((Z)-2-(2-(2,6-dichlorophenylamino)benzyloxyimino)p...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207448(2-(2',6'-diethoxy-2-fluoro-biphenyl4-yl)-propionic...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207445(CHEMBL254377 | N-(2-(1-(4-bromobenzyl)-5-methoxy-2...)
Affinity DataIC50: >6.60E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM22966(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >6.60E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM22967(2-phenylethyl 2-{1-[(4-chlorophenyl)carbonyl]-5-me...)
Affinity DataIC50: >6.60E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute For Chemical Biology And Center In Molecular Toxicology

Curated by ChEMBL
LigandPNGBDBM50207449(2-(1-(4-bromobenzyl)-5-methoxy-2-methyl-1H-indol-3...)
Affinity DataIC50: >6.60E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed