Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50048896
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50009568((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...)
Affinity DataIC50:  640nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230627(CHEMBL10519)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50009568((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...)
Affinity DataIC50:  1.40E+3nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50005478(2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-ph...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230630(CHEMBL10144)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230635(CHEMBL10642)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230622(CHEMBL274212)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50212289(CHEMBL10121)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  2.50E+3nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230626(CHEMBL10703)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230627(CHEMBL10519)
Affinity DataIC50:  2.60E+3nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230631(CHEMBL275976)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50212303(CHEMBL10215)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50005478(2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-ph...)
Affinity DataIC50:  3.50E+3nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230625(CHEMBL10686)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230628(CHEMBL273261)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230633(CHEMBL10559)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50212300(CHEMBL10127)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230629(CHEMBL10405)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230632(CHEMBL10185)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50212289(CHEMBL10121)
Affinity DataIC50:  7.70E+3nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230624(CHEMBL269215)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50212303(CHEMBL10215)
Affinity DataIC50:  1.10E+4nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50212300(CHEMBL10127)
Affinity DataIC50:  3.00E+4nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230623(CHEMBL10255)
Affinity DataIC50: >4.00E+4nMAssay Description:Concentration required to inhibit the extent of glutamate-dependent tubulin polymerization by 50% at 37 degrees C(1.0 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230623(CHEMBL10255)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50230634(CHEMBL10653)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of glutamate-dependent tubulin polymerization at 30 degrees C(0.25 mM MgCl2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed