Affinity DataIC50: 1.5nMAssay Description:Inhibition of Mycobacterium avium DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of rat liver DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 9.73nMAssay Description:Inhibition of Mycobacterium avium DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of Toxoplasma gondii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMpH: 7.4Assay Description:Inhibition of human DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of Pneumocystis carinii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of Pneumocystis carinii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 170nMpH: 7.4Assay Description:Inhibition of Toxoplasma gondii DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMpH: 7.4Assay Description:Inhibition of human DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMpH: 7.4Assay Description:Inhibition of human DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMpH: 7.4Assay Description:Inhibition of human DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMpH: 7.4Assay Description:Inhibition of human DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of Mycobacterium avium DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMpH: 7.4Assay Description:Inhibition of human thymidylate synthase at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 460nMpH: 7.4Assay Description:Inhibition of Toxoplasma gondii DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 540nMpH: 7.4Assay Description:Inhibition of human thymidylate synthase at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 900nMpH: 7.4Assay Description:Inhibition of Toxoplasma gondii TS at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMpH: 7.4Assay Description:Inhibition of Toxoplasma gondii TS at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMpH: 7.4Assay Description:Inhibition of Toxoplasma gondii DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMpH: 7.4Assay Description:Inhibition of Toxoplasma gondii DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMpH: 7.4Assay Description:Inhibition of Toxoplasma gondii TS at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMpH: 7.4Assay Description:Inhibition of human DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMpH: 7.4Assay Description:Inhibition of human thymidylate synthase at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMpH: 7.4Assay Description:Inhibition of human DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of Pneumocystis carinii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+3nMpH: 7.4Assay Description:Inhibition of human thymidylate synthase at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibition of Pneumocystis carinii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibition of rat liver DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Pneumocystis carinii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of rat liver DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of Mycobacterium avium DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Pneumocystis carinii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of Pneumocystis carinii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of rat liver DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMpH: 7.4Assay Description:Inhibition of human DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.34E+4nMAssay Description:Inhibition of Mycobacterium avium DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of Mycobacterium avium DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of Pneumocystis carinii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of rat liver DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.52E+4nMAssay Description:Inhibition of Pneumocystis carinii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of Mycobacterium avium DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of Toxoplasma gondii DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University
Curated by ChEMBL
Duquesne University
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMpH: 7.4Assay Description:Inhibition of Toxoplasma gondii TS at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.84E+4nMAssay Description:Inhibition of Mycobacterium avium DHFR at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+4nMpH: 7.4Assay Description:Inhibition of human thymidylate synthase at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair