Found 51 Enz. Inhib. hit(s) with all data for entry = 50005593 TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 5.00E+4nMAssay Description:Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:Agonist activity at human MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 1.26E+5nMAssay Description:Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 1.60E+4nMAssay Description:Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 1.60E+4nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+4nMAssay Description:Agonist activity at human MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 1.30E+4nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.00E+3nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+3nMAssay Description:Agonist activity at human MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Agonist activity at mouse KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 3.20E+3nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 3.20E+3nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Agonist activity at human MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 2.50E+3nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Agonist activity at human MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 30nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at human MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Agonist activity at mouse KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 7.90E+4nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 5.00E+4nMAssay Description:Agonist activity at mouse KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 3.20E+4nMAssay Description:Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 1.00E+4nMAssay Description:Agonist activity at mouse KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 5.00E+4nMAssay Description:Agonist activity at mouse KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 3.20E+4nMAssay Description:Agonist activity at mouse KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Agonist activity at mouse KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 1.00E+5nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 1.60E+4nMAssay Description:Agonist activity at mouse KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+4nMAssay Description:Agonist activity at human MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+3nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Agonist activity at human MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 1.60E+3nMAssay Description:Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 80nMAssay Description:Agonist activity at human DOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Agonist activity at human MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.30E+3nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 2.50E+4nMAssay Description:Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Agonist activity at mouse MOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataEC50: 1.59E+5nMAssay Description:Agonist activity at mouse KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
