Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50013014
Affinity DataIC50: 8.80nMAssay Description:Inhibition of N-terminal His-tagged p300 HAT (unknown origin) (1287 to 1666 residues) expressed in Escherichia coli using biotinylated H3(1-21) pepti...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of GST-tagged CBP bromodomain (1082 to 1197 residue) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using SGRG-K(Ac)-GG-K ...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of His-FLAG-tagged CBP ( 1082 to 1197 residues) (unknown origin) using H4-tetraAc-biotin as substrate incubated for 20 mins by AlphaLISA a...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of His-tagged CBP bromodomain (unknown origin) using H2N-ALREIRRYQK(Ac)STELLIRKLK-(biotin)-COOH as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of N-terminal His/GST-tagged human p300 HAT (965 to 1810 residues) expressed in Sf9 insect cells using H3 peptide as substrate in presence...More data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibition of His-FLAG-tagged CBP ( 1082 to 1197 residues) (unknown origin) using H4-tetraAc-biotin as substrate incubated for 20 mins by AlphaLISA a...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal GST-fused human P300 (1284 to1673 residues) catalytic domain expressed in sf9 insect cells using histone H3 and [acetyl-3H]-...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of N-terminal His/GST-tagged human p300 HAT (965 to 1810 residues) expressed in Sf9 insect cells using H3 peptide as substrate in presence...More data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Inhibition of N-terminal His/GST-tagged human p300 HAT (965 to 1810 residues) expressed in Sf9 insect cells using H3 peptide as substrate in presence...More data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Inhibition of His-tagged CBP bromodomain (unknown origin) using H2N-ALREIRRYQK(Ac)STELLIRKLK-(biotin)-COOH as substrate preincubated for 30 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 774nMAssay Description:Inhibition of human GST-tagged CBP BrD (1082 to 1197 residues) expressed in Escherichia coli BL21 (DE3) cells using N-C: SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac...More data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of N-terminal His/GST-tagged human p300 HAT (965 to 1810 residues) expressed in Sf9 insect cells using H3 peptide as substrate in presence...More data for this Ligand-Target Pair
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of P300 catalytic domain (unknown origin) using histone H3 and [acetyl-3H]-acetylcoenzyme A as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of N-terminal GST-tagged human CBP HAT(1319 to 1710 residues) expressed in Escherichia coli using histone H3 (1 to 21 residues) as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of GST-tagged CBP bromodomain (1082 to 1197 residue) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using SGRG-K(Ac)-GG-K ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of N-terminal His-tagged p300 HAT (unknown origin) (1287 to 1666 residues) expressed in Escherichia coli using biotinylated H3(1-21) pepti...More data for this Ligand-Target Pair
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of N-terminal GST-tagged human CBP HAT(1319 to 1710 residues) expressed in Escherichia coli using histone H3 (1 to 21 residues) as substra...More data for this Ligand-Target Pair
Affinity DataIC50: 4.85E+3nMAssay Description:Inhibition of N-terminal His/GST-tagged human p300 HAT (965 to 1810 residues) expressed in Sf9 insect cells using H3 peptide as substrate in presence...More data for this Ligand-Target Pair
Affinity DataIC50: 5.35E+3nMAssay Description:Inhibition of N-terminal His-tagged human p300 HAT (1319 to 1710 residues) expressed in Escherichia coli using histone H3 (1 to 21 residues) as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 5.92E+3nMAssay Description:Inhibition of N-terminal His-tagged human p300 HAT (1319 to 1710 residues) expressed in Escherichia coli using histone H3 (1 to 21 residues) as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 8.39E+3nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged GCN5 HAT domain (362 to 837 residues) expressed in baculovirus infected Sf9 cells using histon...More data for this Ligand-Target Pair
Affinity DataIC50: 9.74E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PCAF HAT domain (493 to 657 residues) expressed in Escherichia coli (BL21 D3) using histone H3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.75E+4nMAssay Description:Inhibition of human P300 (1284 to1673 residues) catalytic domain using histone H3 and [acetyl-3H]-acetylcoenzyme A as substrate incubated for 1 hr by...More data for this Ligand-Target Pair
Affinity DataIC50: 8.74E+4nMAssay Description:Inhibition of recombinant human C-terminal FLAG-tagged GCN5 HAT domain (362 to 837 residues) expressed in baculovirus infected Sf9 cells using histon...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PCAF HAT domain (493 to 657 residues) expressed in Escherichia coli (BL21 D3) using histone H3 ...More data for this Ligand-Target Pair
Affinity DataKd: 470nMAssay Description:Binding affinity to human His-Tev tagged EP300 expressed in bacterial expression system incubated for 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 2.26E+4nMAssay Description:Binding affinity to human His-Tev tagged EP300 expressed in bacterial expression system incubated for 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Binding affinity to human His-Tev tagged CBP expressed in bacterial expression system incubated for 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 1.81E+4nMAssay Description:Binding affinity to human His-Tev tagged CBP expressed in bacterial expression system incubated for 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+3nMAssay Description:Inhibition of NanoLuc tagged CBP bromodomain (unknown origin) expressed in HEK293 cells harboring Halo-tagged histone H3.3 by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 530nMAssay Description:Inhibition of NanoLuc tagged CBP bromodomain (unknown origin) expressed in HEK293 cells harboring Halo-tagged histone H3.3 by NanoBRET assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.20E+3nMAssay Description:Binding affinity to human BRD4 bromodomain2 by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 850nMAssay Description:Binding affinity to human BRD4 bromodomain1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 480nMAssay Description:Binding affinity to human BRD4 bromodomain1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 950nMAssay Description:Binding affinity to human BRD4 bromodomain1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Binding affinity to human CBP by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 320nMAssay Description:Binding affinity to human CBP by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 28nMAssay Description:Binding affinity to human CBP by isothermal titration calorimetryMore data for this Ligand-Target Pair
