Found 15 Enz. Inhib. hit(s) with all data for entry = 50013571 TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of MKK4 (unknown origin) by PanQinase assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of MKK4 (unknown origin) by PanQinase assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataIC50: 146nMAssay Description:Inhibition of MKK4 (unknown origin) by PanQinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataKd: 1.10E+3nMAssay Description:Binding affinity to wild-type human partial length MAP4K5 (M1 to P297 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataKd: 5.80nMAssay Description:Binding affinity to wild-type human partial length MAP4K5 (M1 to P297 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataKd: 1.70nMAssay Description:Binding affinity to wild-type human partial length MKK4 (S84 to D399 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataKd: 1.5nMAssay Description:Binding affinity to wild-type human partial length MKK4 (S84 to D399 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataKd: 5.00E+3nMAssay Description:Binding affinity to wild-type human full length MKK7 (M1 to R419 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataKd: 5.00E+3nMAssay Description:Binding affinity to wild-type human full length MKK7 (M1 to R419 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataKd: 5.00E+3nMAssay Description:Binding affinity to wild-type human partial length ZAK (M1 to L331 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataKd: 9.5nMAssay Description:Binding affinity to wild-type human partial length ZAK (M1 to L331 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataKd: 140nMAssay Description:Binding affinity to wild-type human full length JNK1 (M1 to Q384 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataKd: 210nMAssay Description:Binding affinity to wild-type human full length JNK1 (M1 to Q384 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataKd: 450nMAssay Description:Binding affinity to wild-type human partial length BRAF (S429 to E741 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Eberhard Karls Universit£T
Curated by ChEMBL
Eberhard Karls Universit£T
Curated by ChEMBL
Affinity DataKd: 610nMAssay Description:Binding affinity to wild-type human partial length BRAF (S429 to E741 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair
