Compile Data Set for Download or QSAR
maximum 50k data
Found 156 Enz. Inhib. hit(s) with all data for entry = 50016308
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50096906(CHEMBL154745 | US10227373, Compound D-3-Deazaisone...)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of SAH hydrolase (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM155254(US10098888, Compound 2 | US9006242, 2)
Affinity DataKi: <3nMAssay Description:Inhibition of EZH2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594146(CHEMBL5206842)
Affinity DataIC50:  0.00970nMAssay Description:Inhibition of wild-type EZH2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594109(CHEMBL5188827)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594115(CHEMBL5172110)
Affinity DataIC50:  0.0280nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM542469(US11274095, Example 4)
Affinity DataIC50:  0.0380nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM542475(7-chloro-N-((4-chloro-6-methyl-2-oxo-1,2-dihydropy...)
Affinity DataIC50:  0.0390nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50110371(CHEMBL3605441)
Affinity DataIC50:  0.153nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594135(CHEMBL5188577)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of EZH2 Y641N mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594116(CHEMBL5185991)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594114(CHEMBL5191375)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH1(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM588052((2R)-7-chloro-2-[trans-4-(dimethylamino)cyclohexyl...)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of EZH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594135(CHEMBL5188577)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH1(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594132(CHEMBL5197386)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of EZH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50110356(CHEMBL3605456)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of EZH2 (unknown origin) using histone H3 as substrate by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594113(CHEMBL5204709)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594148(CHEMBL5207948)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of wild-type EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594147(CHEMBL5203091)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594135(CHEMBL5188577)
Affinity DataIC50:  0.680nMAssay Description:Inhibition of wild-type EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594148(CHEMBL5207948)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50110371(CHEMBL3605441)
Affinity DataIC50:  0.795nMAssay Description:Inhibition of wild-type EZH2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594146(CHEMBL5206842)
Affinity DataIC50:  0.920nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594145(CHEMBL5188124)
Affinity DataIC50:  0.930nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594147(CHEMBL5203091)
Affinity DataIC50:  1nMAssay Description:Inhibition of wild-type EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50563825(CHEMBL4794859)
Affinity DataIC50: <1nMAssay Description:Inhibition of wild-type EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50563825(CHEMBL4794859)
Affinity DataIC50: <1nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594137(CHEMBL5205079)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of wild-type EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594145(CHEMBL5188124)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of wild-type EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594142(CHEMBL5195001)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM378907(5,8-dichloro-7-(3,5-dimethylisoxazol-4-yl)-2-((7-m...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM588052((2R)-7-chloro-2-[trans-4-(dimethylamino)cyclohexyl...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594146(CHEMBL5206842)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of EZH2 (unknown origin) assessed as reduction in H3K27me3 levelMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594127(CHEMBL5192941)
Affinity DataIC50:  3nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594118(CHEMBL5205712)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594144(CHEMBL5193217)
Affinity DataIC50: <5nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594134(CHEMBL5187783)
Affinity DataIC50: <5nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594143(CHEMBL5190398)
Affinity DataIC50: <5nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM464542(US10793549, Compound G-28)
Affinity DataIC50:  5nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594155(CHEMBL5203667)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594124(CHEMBL5186430)
Affinity DataIC50:  7nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH1(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594116(CHEMBL5185991)
Affinity DataIC50:  7nMAssay Description:Inhibition of EZH1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50110350(CHEMBL3605446)
Affinity DataIC50:  7nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50544756(CHEMBL4637350)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594132(CHEMBL5197386)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of EZH2 (unknown origin) assessed as reduction in H3K27me3 levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM190196(EPZ008277 | US9175331, 25)
Affinity DataIC50:  8nMAssay Description:Inhibition of wild-type EZH2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594136(CHEMBL5190244)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM155255(US10098888, Compound 105 | US11642348, Compound 10...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM588052((2R)-7-chloro-2-[trans-4-(dimethylamino)cyclohexyl...)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of EZH2 (unknown origin) assessed as reduction in H3K27me3 levelMore data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594138(CHEMBL5173929)
Affinity DataIC50:  9nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Affiliated Hospital Of Guangdong Medical University

Curated by ChEMBL
LigandPNGBDBM50594154(CHEMBL5178720)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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