Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with all data for entry = 3401
TargetProthrombin(Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32657(benzamidine- based compound, 6)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic inhibition of human thrombin was determined photometrically at 405 nm using the chromogenic substrate Pefachrom tPa. Reactions were performed...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32656(benzamidine- based compound, 5)
Affinity DataKi:  4nM ΔG°:  -47.9kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic inhibition of human thrombin was determined photometrically at 405 nm using the chromogenic substrate Pefachrom tPa. Reactions were performed...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32654(m-chlorobenzylamide, 3)
Affinity DataKi:  47nM ΔG°:  -41.8kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic inhibition of human thrombin was determined photometrically at 405 nm using the chromogenic substrate Pefachrom tPa. Reactions were performed...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32658(m-chlorobenzylamide, 7)
Affinity DataKi:  100nM ΔG°:  -40.0kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic inhibition of human thrombin was determined photometrically at 405 nm using the chromogenic substrate Pefachrom tPa. Reactions were performed...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32655(benzamidine- based compound, 4)
Affinity DataKi:  180nM ΔG°:  -38.5kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic inhibition of human thrombin was determined photometrically at 405 nm using the chromogenic substrate Pefachrom tPa. Reactions were performed...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32653(m-chlorobenzylamide, 2)
Affinity DataKi:  180nM ΔG°:  -38.5kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic inhibition of human thrombin was determined photometrically at 405 nm using the chromogenic substrate Pefachrom tPa. Reactions were performed...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32652(m-chlorobenzylamide, 1)
Affinity DataKi:  6.80E+3nM ΔG°:  -29.5kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic inhibition of human thrombin was determined photometrically at 405 nm using the chromogenic substrate Pefachrom tPa. Reactions were performed...More data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Philipps University Marburg

LigandPNGBDBM32659(m-chlorobenzylamide, 8)
Affinity DataKi:  8.70E+3nM ΔG°:  -28.9kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic inhibition of human thrombin was determined photometrically at 405 nm using the chromogenic substrate Pefachrom tPa. Reactions were performed...More data for this Ligand-Target Pair