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Found 125 Enz. Inhib. hit(s) with all data for entry = 8870
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM148977(US10512644, Compound Morphine | US8962646, A)
Affinity DataKi:  8.44nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  14.3nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425895(US10512644, Compound alpha-6-mPEG1-O-Morphine)
Affinity DataKi:  15.7nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425934(US10512644, Compound 6-O-mPEG4-Nalbuphine)
Affinity DataKi:  17.5nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425896(US10512644, Compound alpha-6-mPEG2-O-Morphine)
Affinity DataKi:  22nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425898(US10512644, Compound alpha-6-mPEG4-O-Morphine)
Affinity DataKi:  23.1nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  25.9nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425933(US10512644, Compound 6-O-mPEG3-Nalbuphine)
Affinity DataKi:  27.4nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425935(US10512644, Compound 6-O-mPEG5-Nalbuphine)
Affinity DataKi:  35.1nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425935(US10512644, Compound 6-O-mPEG5-Nalbuphine)
Affinity DataKi:  35.6nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425899(US10512644, Compound alpha-6-mPEG5-O-Morphine)
Affinity DataKi:  39.4nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425936(US10512644, Compound 6-O-mPEG6-Nalbuphine)
Affinity DataKi:  44.3nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425897(US10512644, Compound alpha-6-mPEG3-O-Morphine)
Affinity DataKi:  50.7nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425901(US10512644, Compound alpha-6-mPEG7-O-Morphine)
Affinity DataKi:  56.9nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425900(US10512644, Compound alpha-6-mPEG6-O-Morphine)
Affinity DataKi:  73nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425937(US10512644, Compound 6-O-mPEG7-Nalbuphine)
Affinity DataKi:  77.9nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425938(US10512644, Compound 6-O-mPEG8-Nalbuphine)
Affinity DataKi:  79.5nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425902(US10512644, Compound alpha-6-mPEG9-O-Morphine)
Affinity DataKi:  111nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM148977(US10512644, Compound Morphine | US8962646, A)
Affinity DataKi:  118nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425939(US10512644, Compound 6-O-mPEG9-Nalbuphine)
Affinity DataKi:  122nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425936(US10512644, Compound 6-O-mPEG6-Nalbuphine)
Affinity DataKi:  130nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425903(US10512644, Compound Oxycodone)
Affinity DataKi:  133nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425935(US10512644, Compound 6-O-mPEG5-Nalbuphine)
Affinity DataKi:  148nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425934(US10512644, Compound 6-O-mPEG4-Nalbuphine)
Affinity DataKi:  149nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425939(US10512644, Compound 6-O-mPEG9-Nalbuphine)
Affinity DataKi:  158nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425933(US10512644, Compound 6-O-mPEG3-Nalbuphine)
Affinity DataKi:  163nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425938(US10512644, Compound 6-O-mPEG8-Nalbuphine)
Affinity DataKi:  168nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425939(US10512644, Compound 6-O-mPEG9-Nalbuphine)
Affinity DataKi:  186nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425933(US10512644, Compound 6-O-mPEG3-Nalbuphine)
Affinity DataKi:  218nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425936(US10512644, Compound 6-O-mPEG6-Nalbuphine)
Affinity DataKi:  247nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425937(US10512644, Compound 6-O-mPEG7-Nalbuphine)
Affinity DataKi:  314nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM50105085(17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alp...)
Affinity DataKi:  319nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425937(US10512644, Compound 6-O-mPEG7-Nalbuphine)
Affinity DataKi:  346nMAssay Description:Briefly, the receptor binding affinity of the nalbuphine and PEG-nalbuphine conjugates was measured using radioligand binding assays in CHO cells tha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425896(US10512644, Compound alpha-6-mPEG2-O-Morphine)
Affinity DataKi:  404nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425898(US10512644, Compound alpha-6-mPEG4-O-Morphine)
Affinity DataKi:  439nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425895(US10512644, Compound alpha-6-mPEG1-O-Morphine)
Affinity DataKi:  445nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425899(US10512644, Compound alpha-6-mPEG5-O-Morphine)
Affinity DataKi:  558nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425897(US10512644, Compound alpha-6-mPEG3-O-Morphine)
Affinity DataKi:  576nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425905(US10512644, Compound alpha-6-mPEG2-O-Hydroxycodone)
Affinity DataKi:  632nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425904(US10512644, Compound alpha-6-mPEG1-O-Hydroxycodone)
Affinity DataKi:  654nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425901(US10512644, Compound alpha-6-mPEG7-O-Morphine)
Affinity DataKi:  670nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425900(US10512644, Compound alpha-6-mPEG6-O-Morphine)
Affinity DataKi:  774nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425906(US10512644, Compound alpha-6-mPEG3-O-Hydroxycodone)
Affinity DataKi:  775nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425907(US10512644, Compound alpha-6-mPEG4-O-Hydroxycodone)
Affinity DataKi:  893nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425902(US10512644, Compound alpha-6-mPEG9-O-Morphine)
Affinity DataKi:  1.25E+3nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425914(US10512644, Compound alpha-6-mPEG2-O-Codeine)
Affinity DataKi:  1.38E+3nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425910(US10512644, Compound alpha-6-mPEG7-O-Hydroxycodone)
Affinity DataKi:  1.61E+3nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425913(US10512644, Compound alpha-6-mPEG1-O-Codeine)
Affinity DataKi:  1.82E+3nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425908(US10512644, Compound alpha-6-mPEG5-O-Hydroxycodone)
Affinity DataKi:  1.86E+3nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Inheris Pharmaceuticals

US Patent
LigandPNGBDBM425909(US10512644, Compound alpha-6-mPEG6-O-Hydroxycodone)
Affinity DataKi:  1.90E+3nMAssay Description:Briefly, serial dilutions of the test compounds were placed in a 96-well plate to which were added SPA beads, membrane and radioligand. The assay con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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