Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50000673
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50088381(ADL 8-2698 | Alvimopan | Entereg)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257769(CHEMBL4100902)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257771(CHEMBL4075084)
Affinity DataIC50:  661nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257774(CHEMBL4104814)
Affinity DataIC50:  794nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257770(CHEMBL4096255)
Affinity DataIC50:  1.29E+3nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257772(CHEMBL4081855)
Affinity DataIC50:  1.62E+3nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkem Laboratories

Curated by ChEMBL
LigandPNGBDBM50257773(CHEMBL4081523)
Affinity DataIC50:  2.34E+3nMAssay Description:Antagonist activity at recombinant human MOR expressed in HEK293T cells assessed as reduction in DAMGO-induced inhibition of forskolin-stimulated cAM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed