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Found 8 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50035106
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085506((1R,3S)-5-Methylene-3-p-tolyl-7-aza-tricyclo[5.3.0...)
Affinity DataIC50:  2.20nMAssay Description:The compound was tested for inhibition of [3H]norepinephrine uptake in HEK cells by expressing cDNA for human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085504((1R,3S,5R)-5-Phenyl-3-p-tolyl-7-aza-tricyclo[5.3.0...)
Affinity DataIC50:  11nMAssay Description:The compound was tested for inhibition of [3H]norepinephrine uptake in HEK cells by expressing cDNA for human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085503((1R,3S,5S)-5-Propyl-3-p-tolyl-7-aza-tricyclo[5.3.0...)
Affinity DataIC50:  18nMAssay Description:The compound was tested for inhibition of [3H]norepinephrine uptake in HEK cells by expressing cDNA for human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085505((1R,3S,5R)-5-(4-Chloro-phenyl)-3-p-tolyl-7-aza-tri...)
Affinity DataIC50:  23nMAssay Description:The compound was tested for inhibition of [3H]norepinephrine uptake in HEK cells by expressing cDNA for human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085502((4S,6S)-3-Butyl-4-p-tolyl-1-aza-tricyclo[4.4.0.0*2...)
Affinity DataIC50:  109nMAssay Description:The compound was tested for inhibition of [3H]norepinephrine uptake in HEK cells by expressing cDNA for human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085507((1R,3S)-3-p-Tolyl-7-aza-tricyclo[5.3.0.0*4,8*]deca...)
Affinity DataIC50:  110nMAssay Description:The compound was tested for inhibition of [3H]norepinephrine uptake in HEK cells by expressing cDNA for human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085508((1R,3S,5S)-5-Methyl-3-p-tolyl-7-aza-tricyclo[5.3.0...)
Affinity DataIC50:  296nMAssay Description:The compound was tested for inhibition of [3H]norepinephrine uptake in HEK cells by expressing cDNA for human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50085501((1R,3S)-3-(4-Fluoro-phenyl)-7-aza-tricyclo[5.3.0.0...)
Affinity DataIC50:  620nMAssay Description:The compound was tested for inhibition of [3H]norepinephrine uptake in HEK cells by expressing cDNA for human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed