TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human aldosterone synthase expressed in V79 MZ cells pretreated with compound for 1 hr followed by addition of 500 nM 11-deoxycorticost...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human aldosterone synthase expressed in V79 MZ cells pretreated with compound for 1 hr followed by addition of 500 nM 11-deoxycorticost...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human aldosterone synthase expressed in V79 MZ cells pretreated with compound for 1 hr followed by addition of 500 nM 11-deoxycorticost...More data for this Ligand-Target Pair
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Saarland University And Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by ChEMBL
Affinity DataIC50: 208nMAssay Description:Inhibition of human aldosterone synthase expressed in V79 MZ cells pretreated with compound for 1 hr followed by addition of 500 nM 11-deoxycorticost...More data for this Ligand-Target Pair