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Found 16 Enz. Inhib. hit(s) with all data for assayid = 18 entry = 50048253
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210257(CHEMBL3961053)
Affinity DataIC50:  0.970nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210177(ONX-0803 | Pacritinib | SB-1518 | SB1518)
Affinity DataIC50:  1nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210176(CHEMBL3924682)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210167(CHEMBL3917405)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210174(CHEMBL3915689)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210190(CHEMBL3964125)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210254(CHEMBL3980203)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210258(CHEMBL3920872)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210262(CHEMBL3951291)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210179(CHEMBL3942555)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210175(CHEMBL3945293)
Affinity DataIC50:  5nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210178(CHEMBL3933593)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210261(CHEMBL3952364)
Affinity DataIC50:  9nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210173(CHEMBL3972157)
Affinity DataIC50:  30nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210263(CHEMBL3954183)
Affinity DataIC50: <39nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
National University Of Singapore

Curated by ChEMBL
LigandPNGBDBM50210180(CHEMBL3981879)
Affinity DataIC50:  47nMAssay Description:Inhibition of JAK2 (unknown origin) preincubated for 20 mins followed by [33P]ATP addition measured after 120 mins by Hotspot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed