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Found 7 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 2251
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18621(1-(2-{[(18Z)-13-hydroxy-12-methoxy-3,5,5-trimethyl...)
Affinity DataIC50:  0.300nM EC50:  0.600nMpH: 7.5Assay Description:GR-Mediated Agonist Activity Assay- GR-mediated activation by compounds is measured against maximal activation of dexamethasone in the same experimen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18624((18Z)-18-({3-[(1E)-1-(ethoxyimino)ethyl]thiophen-2...)
Affinity DataIC50:  0.5nM EC50:  0.400nMpH: 7.5Assay Description:GR-Mediated Agonist Activity Assay- GR-mediated activation by compounds is measured against maximal activation of dexamethasone in the same experimen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18620(2-{[(18Z)-13-hydroxy-12-methoxy-3,5,5-trimethyl-17...)
Affinity DataIC50:  0.800nM EC50:  0.200nMpH: 7.5Assay Description:GR-Mediated Agonist Activity Assay- GR-mediated activation by compounds is measured against maximal activation of dexamethasone in the same experimen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18619((18Z)-12-methoxy-3,5,5-trimethyl-18-[(3-{[(2,2,2-t...)
Affinity DataIC50:  0.900nM EC50:  0.5nMpH: 7.5Assay Description:GR-Mediated Agonist Activity Assay- GR-mediated activation by compounds is measured against maximal activation of dexamethasone in the same experimen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18618((18Z)-18-({3-[(2-hydroxyethoxy)methyl]thiophen-2-y...)
Affinity DataIC50:  1nM EC50:  1.60nMpH: 7.5Assay Description:GR-Mediated Agonist Activity Assay- GR-mediated activation by compounds is measured against maximal activation of dexamethasone in the same experimen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18615((18Z)-12-methoxy-3,5,5-trimethyl-18-{[3-(piperidin...)
Affinity DataIC50:  1nM EC50:  0.300nMpH: 7.5Assay Description:GR-Mediated Agonist Activity Assay- GR-mediated activation by compounds is measured against maximal activation of dexamethasone in the same experimen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM18625(Ester, 27 | methyl 2-{[(18Z)-13-hydroxy-12-methoxy...)
Affinity DataIC50:  1.80nM EC50:  1.40nMpH: 7.5Assay Description:GR-Mediated Agonist Activity Assay- GR-mediated activation by compounds is measured against maximal activation of dexamethasone in the same experimen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed