Affinity DataKi: 220nM IC50: 30nMpH: 7.4Assay Description:Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in 10 mM phosphate-buffered saline (pH 7.4). IC50, defined as t...More data for this Ligand-Target Pair
TargetBeta-lactamase(Klebsiella pneumoniae)
National Institute Of Health Dr. Ricardo Jorge Av. Padre Cruz
Curated by ChEMBL
National Institute Of Health Dr. Ricardo Jorge Av. Padre Cruz
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Klebsiella pneumoniae Beta-Lactamase SHV-72More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of Klebsiella pneumoniae Beta-Lactamase SHV-1More data for this Ligand-Target Pair
Affinity DataIC50: 133nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 222nMpH: 7.0 T: 2°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 222nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair