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TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50047418(CHEMBL3319223)
Affinity DataIC50:  3.40nMAssay Description:Displacement of [125I]human ghrelin from rat GHS-R1a expressed in HEK cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50366958(CHEMBL1790587)
Affinity DataIC50:  6.30nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 5bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against histone deacetylase (HDAC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50146077(CHEMBL3763388)
Affinity DataIC50:  18nMAssay Description:Inhibition of HDAC in rat liver by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 12aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50146076(CHEMBL3764525)
Affinity DataIC50:  21nMAssay Description:Inhibition of HDAC in rat liver by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 5bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50154337(6-((5S,11S,13aR)-5-benzyl-8,8-dimethyl-4,7,10,13-t...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 5bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 5aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475567(6-Benzenesulfonylhexanoic Acid Hydroxamide | CHEMB...)
Affinity DataIC50:  40nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50366958(CHEMBL1790587)
Affinity DataIC50:  56nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475570(6-Benzenesulfinylhexanoic Acid Hydroxamide | CHEMB...)
Affinity DataIC50:  60nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082325(CHEMBL99392)
Affinity DataIC50:  66nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 5bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082665(4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  78nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50366958(CHEMBL1790587)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475559(CHEMBL371212)
Affinity DataIC50:  110nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475566(6-Phenylsulfanylhexanoic Acid Hydroxamide | CHEMBL...)
Affinity DataIC50:  120nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50154337(6-((5S,11S,13aR)-5-benzyl-8,8-dimethyl-4,7,10,13-t...)
Affinity DataIC50:  137nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082665(4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  148nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475565(6-(4-Chlorophenylsulfinyl)Hexanoic Acid Hydroxamid...)
Affinity DataIC50:  150nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082666(4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]b...)
Affinity DataIC50:  152nMAssay Description:Inhibitory activity against histone deacetylase (HDAC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082666(4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]b...)
Affinity DataIC50:  153nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475562(CHEMBL383285)
Affinity DataIC50:  160nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475558(6-(4-Dimethylaminophenylsulfinyl)Hexanoic Acid Hyd...)
Affinity DataIC50:  180nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082666(4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]b...)
Affinity DataIC50:  216nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50154337(6-((5S,11S,13aR)-5-benzyl-8,8-dimethyl-4,7,10,13-t...)
Affinity DataIC50:  226nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475557(CHEMBL203421)
Affinity DataIC50:  240nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082657(4-Dimethylamino-N-(7-hydroxycarbamoyl-heptyl)-benz...)
Affinity DataIC50:  241nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 5bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082657(4-Dimethylamino-N-(7-hydroxycarbamoyl-heptyl)-benz...)
Affinity DataIC50:  256nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475556(6-(4-Chlorophenylsulfanyl)Hexanoic Acid Hydroxamid...)
Affinity DataIC50:  260nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475563(CHEMBL199713)
Affinity DataIC50:  310nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475561(CHEMBL380339)
Affinity DataIC50:  340nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082325(CHEMBL99392)
Affinity DataIC50:  349nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50220740(CHEMBL55974)
Affinity DataIC50:  359nMAssay Description:Inhibitory activity against histone deacetylase (HDAC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475569(7-(4-Chlorophenylsulfinyl)Heptanoic Acid Hydroxami...)
Affinity DataIC50:  380nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475564(CHEMBL381561)
Affinity DataIC50:  390nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475560(CHEMBL203036)
Affinity DataIC50:  400nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475568(CHEMBL201075)
Affinity DataIC50:  410nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082325(CHEMBL99392)
Affinity DataIC50:  411nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  440nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082657(4-Dimethylamino-N-(7-hydroxycarbamoyl-heptyl)-benz...)
Affinity DataIC50:  488nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082666(4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]b...)
Affinity DataIC50:  640nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 5aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475571(CHEMBL199665)
Affinity DataIC50:  700nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50146075(CHEMBL3765502)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of HDAC in rat liver by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition concentration required to inhibit rat liver histone deacetylase (HDAC) in the presence of compound 5e as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50082665(4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)...)
Affinity DataIC50:  3.51E+3nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 5bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50220741(CHEMBL417594)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibitory activity against histone deacetylase (HDAC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50475572(CHEMBL380443)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of HDAC in rat liver homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed