Compile Data Set for Download or QSAR
maximum 50k data
Found 15 of ec50 data for polymerid = 49000621
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126761((S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at GluK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50088222((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...)
Affinity DataEC50:  2.50E+3nMAssay Description:Compound was tested for agonistic activity at Glutamate receptor 6 using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50088222((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at GluK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50088222((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...)
Affinity DataEC50:  2.50E+3nMAssay Description:Effective concentration against GluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50088197(CHEMBL58590 | E-2-Amino-4-[3-(4-chloro-phenyl)-all...)
Affinity DataEC50:  2.80E+3nMAssay Description:Effective concentration of the compound required for evoking response in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50088216(CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...)
Affinity DataEC50:  3.30E+3nMAssay Description:Effective concentration against GluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50088213((2S,4R)-4-allyl glutamate | 2-Allyl-4-amino-pentan...)
Affinity DataEC50:  4.40E+3nMAssay Description:Effective concentration of the compound required for evoking response in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50088212(2-Amino-4-but-2-enyl-pentanedioic acid(LY339180) |...)
Affinity DataEC50:  4.50E+3nMAssay Description:Effective concentration of the compound required for evoking response in HEK293 cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091477((S)-2-Amino-4-cyclopentylidene-pentanedioic acid |...)
Affinity DataEC50:  6.20E+3nMAssay Description:Compound was tested for agonistic activity at Glutamate receptor 5 using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091481((S)-2-Amino-4-propylidene-pentanedioicacid | CHEMB...)
Affinity DataEC50:  1.42E+4nMAssay Description:Compound was tested for agonistic activity at Glutamate receptor 5 using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataEC50:  1.62E+4nMAssay Description:Compound was tested for agonistic activity at Glutamate receptor 5 using HEK293 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50002369((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...)
Affinity DataEC50:  1.62E+4nMAssay Description:Effective concentration against GluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataEC50:  2.20E+4nMAssay Description:Induction of calcium influx in HEK293 cells expressing human GLUK5 by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataEC50:  7.50E+4nMAssay Description:Compound was tested for agonistic activity at Glutamate receptor 6 using HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...)
Affinity DataEC50:  7.50E+4nMAssay Description:Effective concentration against GluR5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed