Compile Data Set for Download or QSAR
Report error Found 108 Enz. Inhib. hit(s) with all data for entry = 278
TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 7009BDBM7009(2-(3-methyl-2,6-dioxopiperidin-3-yl)-4-((3- (pheno...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4210BDBM4210(4-((6-(2-(dimethylamino)ethoxy)-4- phenoxypyridin-...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4212BDBM4212(4-((6-cyclopropyl-1-(tetrahydro-2H-pyran- 4-yl)-1H...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4385BDBM4385(4-((6-(2-(difluoromethyl)pyridin-4-yl)-1- (tetrahy...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4389BDBM4389(2-(2,6-dioxopiperidin-3-yl)-4-((2-methoxy- 4-(2-(p...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4393BDBM4393(2-(2,6-dioxopiperidin-3-yl)-4-((6-(3-fluoro- 4-met...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4537BDBM4537(2-(2,6-dioxopiperidin-3-yl)-4-((1-methyl-6- phenox...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4541BDBM4541(2-(2,6-dioxopiperidin-3-yl)-4-((6-(3- fluorophenox...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 5596BDBM5596((S)-2-(2,6-dioxopiperidin-3-yl)-4-((1- methyl-6-(2...)
Affinity DataEC50: <10nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4721BDBM4721(2-(2,6-dioxopiperidin-3-yl)-4-((6-methoxy- 1-(tetr...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 5925BDBM5925(4-((6-cyclopropyl-1-methyl-2-oxo-1,2,3,4- tetrahyd...)
Affinity DataEC50: <10nMAssay Description:The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4726BDBM4726(2-(2,6-dioxopiperidin-3-yl)-4-((1-methyl-6- (2-met...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4824BDBM4824(2-(2,6-dioxopiperidin-3-yl)-4-((4-methyl-1- (tetra...)
Affinity DataEC50: <10nMAssay Description:The HEK293 cells were co-transfected with DNA construct containing PPARdelta-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4834BDBM4834(2-(2,6-dioxopiperidin-3-yl)-4-((6-methyl-4- phenox...)
Affinity DataEC50: <10nMAssay Description:The HEK293 cells were co-transfected with DNA construct containing PPARdelta-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6128BDBM6128(2-(2,6-dioxopiperidin-3-yl)-4-((1-methyl-6- (1-met...)
Affinity DataEC50: <10nMAssay Description:Kd values were obtained by incubating His-PPARgamma-LBD with biotinylated peptide, europium-labeled anti-histidine antibody, and allophycocyanin-labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6130BDBM6130((S)-4-((6-(1-cyclopropyl-1H-pyrazol-4-yl)- 1-methy...)
Affinity DataEC50: <10nMAssay Description:Kd values were obtained by incubating His-PPARgamma-LBD with biotinylated peptide, europium-labeled anti-histidine antibody, and allophycocyanin-labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4975BDBM4975(4-((1,2-dimethyl-6-(2-methylpyridin-4-yl)- 1H-benz...)
Affinity DataEC50: <10nMAssay Description:The HEK293 cells were co-transfected with DNA construct containing PPARdelta-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6130BDBM6130((S)-4-((6-(1-cyclopropyl-1H-pyrazol-4-yl)- 1-methy...)
Affinity DataEC50: <10nMAssay Description:Kd values were obtained by incubating His-PPARgamma-LBD with biotinylated peptide, europium-labeled anti-histidine antibody, and allophycocyanin-labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 5167BDBM5167(2-(2,6-dioxopiperidin-3-yl)-4-((1-methyl-6- (6-met...)
Affinity DataEC50: <10nMAssay Description:The HEK293 cells were co-transfected with DNA construct containing PPARdelta-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6132BDBM6132((S)-4-((6-(1,3-dimethyl-1H-pyrazol-4-yl)- 1-methyl...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6357BDBM6357((S)-4-((6-(2,6-dimethylpyridin-4-yl)-1,3- dimethyl...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6357BDBM6357((S)-4-((6-(2,6-dimethylpyridin-4-yl)-1,3- dimethyl...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6446BDBM6446((S)-4-((1,3-dimethyl-6-(2-methylpyridin-4- yl)-2-o...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6446BDBM6446((S)-4-((1,3-dimethyl-6-(2-methylpyridin-4- yl)-2-o...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6450BDBM6450((S)-2-(2,6-dioxopiperidin-3-yl)-4-((1- methyl-6-(2...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 5241BDBM5241(2-(2,6-dioxopiperidin-3-yl)-4-((1-methyl-6- (3-(tr...)
Affinity DataEC50: <10nMAssay Description:The HEK293 cells were co-transfected with DNA construct containing PPARdelta-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6508BDBM6508(2-(2,6-dioxopiperidin-3-yl)-4-((1-methyl-6- (2-met...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6508BDBM6508(2-(2,6-dioxopiperidin-3-yl)-4-((1-methyl-6- (2-met...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6563BDBM6563(2-(2,6-dioxopiperidin-3-yl)-4-((6-(3-fluoro- 2-met...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6563BDBM6563(2-(2,6-dioxopiperidin-3-yl)-4-((6-(3-fluoro- 2-met...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6565BDBM6565(2-(2,6-dioxopiperidin-3-yl)-4-((6-(5-fluoro- 2-met...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6565BDBM6565(2-(2,6-dioxopiperidin-3-yl)-4-((6-(5-fluoro- 2-met...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6567BDBM6567(4-((6-(3-chloro-2-methylpyridin-4-yl)-1- methyl-2-...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6567BDBM6567(4-((6-(3-chloro-2-methylpyridin-4-yl)-1- methyl-2-...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 165BDBM165(4-((1,2-dimethyl-5-(2-methylpyridin-4-yl)- 1H-benz...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6761BDBM6761(4-((6-(2,6-dimethylpyridin-4-yl)-1-methyl- 2-oxo-1...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 3915BDBM3915(4-((1-cyclopropyl-5-(2-methylpyridin-4- yl)-1H-ben...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6761BDBM6761(4-((6-(2,6-dimethylpyridin-4-yl)-1-methyl- 2-oxo-1...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 3915BDBM3915(4-((1-cyclopropyl-5-(2-methylpyridin-4- yl)-1H-ben...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6764BDBM6764((S)-2-(2,6-dioxopiperidin-3-yl)-4-((6-(2- methoxy-...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6764BDBM6764((S)-2-(2,6-dioxopiperidin-3-yl)-4-((6-(2- methoxy-...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 3917BDBM3917(4-((1,3-dimethyl-6-(2-methylpyridin-4-yl)- 1H-inda...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6774BDBM6774(2-(2,6-dioxopiperidin-3-yl)-4-((6-(3-fluoro- 2-met...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 6853BDBM6853(2-((R)-2,6-dioxopiperidin-3-yl)-4-((6-(2- methylpy...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4204BDBM4204(2-(2,6-dioxopiperidin-3-yl)-4-((5-(2-fluoro- 6-met...)
Affinity DataEC50: <10nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 7004BDBM7004((R)-2-(3-methyl-2,6-dioxopiperidin-3-yl)- 4-((1-me...)
Affinity DataEC50: <10nMAssay Description:EC50 is the concentration of test compounds needed to induce 50% of the maximum luciferase activity in HEK cells transfected with PPAR and Gal4-lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetProtein Wiz(Homo sapiens)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4208BDBM4208(2-(2,6-dioxopiperidin-3-yl)-4-((3-methyl-6- (2-met...)
Affinity DataEC50:  55nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4208BDBM4208(2-(2,6-dioxopiperidin-3-yl)-4-((3-methyl-6- (2-met...)
Affinity DataEC50:  55nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4210BDBM4210(4-((6-(2-(dimethylamino)ethoxy)-4- phenoxypyridin-...)
Affinity DataEC50:  55nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetZinc finger and BTB domain-containing protein 7A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 4389BDBM4389(2-(2,6-dioxopiperidin-3-yl)-4-((2-methoxy- 4-(2-(p...)
Affinity DataEC50:  55nMAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

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