Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50034999
TargetMatrix metalloproteinase-9(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078569((S)-4-(Biphenyl-4-ylmethylsulfanyl)-N-hydroxy-2-[i...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Mouse)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078571((R)-2-[[(Benzhydryl-carbamoyl)-methyl]-(4-methoxy-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory concentration required against matrix metalloprotease-9 (MMP-9 gelatinase B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 2nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Mouse)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078571((R)-2-[[(Benzhydryl-carbamoyl)-methyl]-(4-methoxy-...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Mouse)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)
Affinity DataIC50: 2.5nMAssay Description:Inhibitory concentration required against matrix metalloprotease-9 (MMP-9 gelatinase B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50: 3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078571((R)-2-[[(Benzhydryl-carbamoyl)-methyl]-(4-methoxy-...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Mouse)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078571((R)-2-[[(Benzhydryl-carbamoyl)-methyl]-(4-methoxy-...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078567((S)-N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50: 7nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078570((S)-4-(4-Benzyloxy-benzylsulfanyl)-N-hydroxy-2-[is...)
Affinity DataIC50: 8nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Mouse)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration required against matrix metalloprotease-9 (MMP-9 gelatinase B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50: 12nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 12nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 14nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Mouse)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 15nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078570((S)-4-(4-Benzyloxy-benzylsulfanyl)-N-hydroxy-2-[is...)
Affinity DataIC50: 20nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078569((S)-4-(Biphenyl-4-ylmethylsulfanyl)-N-hydroxy-2-[i...)
Affinity DataIC50: 20nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 25nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078570((S)-4-(4-Benzyloxy-benzylsulfanyl)-N-hydroxy-2-[is...)
Affinity DataIC50: 29nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078569((S)-4-(Biphenyl-4-ylmethylsulfanyl)-N-hydroxy-2-[i...)
Affinity DataIC50: 30nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50: 37nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078567((S)-N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50: 45nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078570((S)-4-(4-Benzyloxy-benzylsulfanyl)-N-hydroxy-2-[is...)
Affinity DataIC50: 49nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078567((S)-N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50: 53nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078568((S)-4-Benzylsulfanyl-2-[(biphenyl-4-sulfonyl)-isob...)
Affinity DataIC50: 90nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078567((S)-N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50: 96nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM8465(CGS 27023 | CHEMBL514138 | hydroxamate analogue 1 ...)
Affinity DataIC50: 96nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078566((S)-4-Benzylsulfanyl-N-hydroxy-2-[isobutyl-(4-meth...)
Affinity DataIC50: 104nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078565((S)-2-[(Biphenyl-4-sulfonyl)-isobutyl-amino]-N-hyd...)
Affinity DataIC50: 156nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50078567((S)-N-Hydroxy-2-[isobutyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50: 384nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed