Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50009187
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  0.710nMAssay Description:In vitro inhibitory activity of the compound against human enzyme thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081092(CHEMBL85238 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibitory activity of the compound against human enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081092(CHEMBL85238 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  1.90nMAssay Description:In vitro inhibitory activity of the compound against human enzyme Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081088(CHEMBL316213 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  3.60nMAssay Description:In vitro inhibitory activity against human prothrombinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081087(CHEMBL87947 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  7.20nMAssay Description:In vitro inhibitory activity of the compound against human enzyme Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081086(CHEMBL314576 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  7.30nMAssay Description:In vitro inhibitory activity of the compound against prothrombinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081090(CHEMBL87502 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  8.60nMAssay Description:In vitro inhibitory activity of the compound against human enzyme Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081092(CHEMBL85238 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  9.90nMAssay Description:In vitro inhibitory activity against human prothrombinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081086(CHEMBL314576 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibitory activity against human prothrombinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081093(CHEMBL88079 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibitory activity of the compound against human enzyme thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081088(CHEMBL316213 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  19nMAssay Description:In vitro inhibitory activity against human prothrombinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  21nMAssay Description:In vitro inhibitory activity of the compound against human enzyme Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081086(CHEMBL314576 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibitory activity of the compound against human enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081090(CHEMBL87502 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  27nMAssay Description:In vitro inhibitory activity against human prothrombinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081088(CHEMBL316213 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  27nMAssay Description:In vitro evaluation of inhibition of cleavage of the chromogenic substrate by human enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081089(CHEMBL315454 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  29nMAssay Description:In vitro inhibitory activity of the compound against human enzyme Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081087(CHEMBL87947 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  35nMAssay Description:In vitro inhibitory activity of the compound against human enzyme Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081089(CHEMBL315454 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  40nMAssay Description:In vitro evaluation of inhibition of cleavage of the chromogenic substrate by human enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081091(CHEMBL316376 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  49nMAssay Description:In vitro inhibitory activity of the compound against human enzyme Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081089(CHEMBL315454 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  64nMAssay Description:In vitro inhibitory activity of the compound against human enzyme Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50:  75nMAssay Description:In vitro inhibitory activity of the compound against human enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081090(CHEMBL87502 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  77nMAssay Description:In vitro evaluation of inhibition of cleavage of the chromogenic substrate by human enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081087(CHEMBL87947 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  110nMAssay Description:In vitro evaluation of inhibition of cleavage of the chromogenic substrate by human enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081091(CHEMBL316376 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  135nMAssay Description:In vitro inhibitory activity of the compound against human enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081086(CHEMBL314576 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  178nMAssay Description:In vitro inhibitory activity of the compound against human enzyme thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081091(CHEMBL316376 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  192nMAssay Description:In vitro inhibitory activity of the compound against human enzyme thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081090(CHEMBL87502 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  235nMAssay Description:In vitro inhibitory activity of the compound against human enzyme thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081088(CHEMBL316213 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50:  285nMAssay Description:In vitro inhibitory activity of the compound against by human enzyme thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081093(CHEMBL88079 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  289nMAssay Description:In vitro inhibitory activity of the compound against human enzyme trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081092(CHEMBL85238 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50:  829nMAssay Description:In vitro inhibitory activity of the compound against human enzyme thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081088(CHEMBL316213 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081089(CHEMBL315454 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081091(CHEMBL316376 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081089(CHEMBL315454 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081087(CHEMBL87947 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081093(CHEMBL88079 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50073429(CHEMBL82032 | CHEMBL84575 | N-((S)-1-Carbamimidoyl...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081087(CHEMBL87947 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081093(CHEMBL88079 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081090(CHEMBL87502 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081092(CHEMBL85238 | N-((S)-1-Carbamimidoyl-2-hydroxy-pip...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Corvas International

Curated by ChEMBL
LigandPNGBDBM50081086(CHEMBL314576 | N-((S)-1-Carbamimidoyl-2-hydroxy-pi...)
Affinity DataIC50: >2.50E+3nMAssay Description:In vitro inhibitory activity of the compound against human enzyme plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed