Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50009469
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50070599(2-Chloro-benzenesulfonic acid 3-(4-guanidino-butox...)
Affinity DataKi:  1.30nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083968(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  4.40nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083963(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  4.70nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083971(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  6nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083969(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  8.30nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083967(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  9.10nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083966(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  9.20nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083961(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  9.40nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083964(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  11nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083957(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  11nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083972(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  20nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083956(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  36nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083960((2E)-2-({1-[(3-(2-cyanobenzenesulfonate)-5-methylp...)
Affinity DataKi:  40nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083962(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  44nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083970((2E)-2-[3-(3-methyl-5-{[2-(trifluoromethyl)benzyl]...)
Affinity DataKi:  420nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083959(3-((4E)-4-{[(E)-amino(imino)methyl]hydrazono}butyl...)
Affinity DataKi:  990nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083965(3-[((2E)-2-{[(E)-amino(imino)methyl]hydrazono}ethy...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083958(3-[((4E)-4-{[(E)-amino(imino)methyl]hydrazono}buty...)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibitory constant against human alpha thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083959(3-((4E)-4-{[(E)-amino(imino)methyl]hydrazono}butyl...)
Affinity DataKi:  1.37E+4nMAssay Description:Compound was evaluated for the inhibitory constant against human Serine protease chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083970((2E)-2-[3-(3-methyl-5-{[2-(trifluoromethyl)benzyl]...)
Affinity DataKi:  1.48E+4nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083971(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083960((2E)-2-({1-[(3-(2-cyanobenzenesulfonate)-5-methylp...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083963(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083962(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  4.50E+4nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083957(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  5.90E+4nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083958(3-[((4E)-4-{[(E)-amino(imino)methyl]hydrazono}buty...)
Affinity DataKi:  6.70E+4nMAssay Description:Inhibitory constant against human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083957(3-[((3E)-3-{[(E)-amino(imino)methyl]hydrazono}prop...)
Affinity DataKi:  8.80E+4nMAssay Description:Compound was evaluated for the inhibitory constant against human Serine protease chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed