Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 1116
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8987BDBM8987(6-chlorotacrine.HCl | CHEMBL486698 | 6-chloro-1,2,...)
Affinity DataIC50: 9.90nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 9002BDBM9002(6-chloro-N-heptyl-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 13nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8989BDBM8989(6-nitro-1,2,3,4-tetrahydroacridin-9-amine | Tacrin...)
Affinity DataIC50: 28nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 9005BDBM9005(6-fluoro-N-heptyl-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 45nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8992BDBM8992(6-fluoro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...)
Affinity DataIC50: 87nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8985BDBM8985(6-methyl-1,2,3,4-tetrahydroacridin-9-amine | Tacri...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 9001BDBM9001(N-heptyl-6-methyl-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 130nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8997BDBM8997(N-benzyl-6-chloro-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 170nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8961BDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 250nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 9003BDBM9003(N-heptyl-6-nitro-1,2,3,4-tetrahydroacridin-9-amine...)
Affinity DataIC50: 290nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8990BDBM8990(6-methoxy-1,2,3,4-tetrahydroacridin-9-amine | Tacr...)
Affinity DataIC50: 350nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 9000BDBM9000(N-heptyl-7-methyl-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 390nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 9004BDBM9004(N-heptyl-6-methoxy-1,2,3,4-tetrahydroacridin-9-ami...)
Affinity DataIC50: 460nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8993BDBM8993(6,7-dichloro-1,2,3,4-tetrahydroacridin-9-amine | T...)
Affinity DataIC50: 470nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8986BDBM8986(7-chloro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...)
Affinity DataIC50: 550nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8996BDBM8996(N-benzyl-6-methyl-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 750nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8998BDBM8998(7-Nitro-9-benzylamino-1,2,3,4-tetrahydroacridine |...)
Affinity DataIC50: 1.60E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8988BDBM8988(7-nitro-1,2,3,4-tetrahydroacridin-9-amine | Tacrin...)
Affinity DataIC50: 3.00E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8995BDBM8995(N-benzyl-7-methyl-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 3.70E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8991BDBM8991(7,9-Diamino-1,2,3,4-tetrahydroacridine | 5,6,7,8-t...)
Affinity DataIC50: 3.80E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8999BDBM8999(N-benzyl-6-nitro-1,2,3,4-tetrahydroacridin-9-amine...)
Affinity DataIC50: 4.80E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8994BDBM8994(6,7-dimethoxy-1,2,3,4-tetrahydroacridin-9-amine | ...)
Affinity DataIC50: 5.20E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandChemical structure of BindingDB Monomer ID 8984BDBM8984(7-methyl-1,2,3,4-tetrahydroacridin-9-amine | Tacri...)
Affinity DataIC50: 8.10E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed