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Found 22 Enz. Inhib. hit(s) with all data for entry = 50009966
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089514(1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration of the compound was tested on Human mGlu4 receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089515(1-Amino-3-phosphono-cyclopent-3-enecarboxylic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration of the compound was tested on Human mGlu4 receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089515(1-Amino-3-phosphono-cyclopent-3-enecarboxylic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Agonistic activity of the compound was tested on Human mGlu4a receptor expressed in recombinant mammalian cells by GTPgammaS binding assay; Partial a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089514(1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Agonistic activity of the compound was tested on Human mGlu4a receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089514(1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration of the compound was tested on Human mGlu2 receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089515(1-Amino-3-phosphono-cyclopent-3-enecarboxylic acid...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089514(1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonistic activity of the compound was tested on Human mGlu2 receptor expressed in recombinant mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089514(1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid...)
Affinity DataEC50: >3.00E+5nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089514(1-Amino-3-phosphono-cyclopent-2-enecarboxylic acid...)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibitory concentration of the compound was tested on Human Metabotropic glutamate receptor 2 expressed in recombinant mammalian cells by GTPgammaS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089518((1R,2R)-1-amino-2-(phosphonomethyl)cyclopropanecar...)
Affinity DataEC50:  7.90E+3nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50021550((1S,3S)-1-amino-3-phosphonocyclopentanecarboxylic ...)
Affinity DataEC50:  2.70E+4nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)
Affinity DataEC50:  500nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
Affinity DataEC50:  4.70E+3nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50021548((1S,3S)-1-amino-3-phosphonocyclopentanecarboxylic ...)
Affinity DataEC50:  8.60E+4nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM66976((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Affinity DataEC50:  3.90E+4nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM17664((2S)-2-amino-3-(phosphonooxy)propanoic acid | CHEM...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089516((1R,2S)-1-amino-2-(phosphonomethyl)cyclopropanecar...)
Affinity DataEC50:  580nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50060137((1R,2S)-4-aminocyclopentane-1,2,4-tricarboxylic ac...)
Affinity DataEC50:  7.00E+3nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089105(1-Amino-3-phosphonomethylene-cyclobutanecarboxylic...)
Affinity DataEC50:  4.40E+3nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089517((1R,2R)-4-Amino-cyclopentane-1,2,4-tricarboxylic a...)
Affinity DataEC50:  9.00E+3nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089515(1-Amino-3-phosphono-cyclopent-3-enecarboxylic acid...)
Affinity DataEC50: >3.00E+5nMAssay Description:Agonistic activity of the compound was tested on Human Metabotropic glutamate receptor 2 expressed in recombinant mammalian cells by GTPgammaS bindin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50089515(1-Amino-3-phosphono-cyclopent-3-enecarboxylic acid...)
Affinity DataEC50:  1.70E+4nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in CHO cells expressing hmGlu4aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed