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Found 6 Enz. Inhib. hit(s) with all data for entry = 11138
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594034((S)-(2-amino-7-(5-(4-isopropoxy-3-(trifluoromethyl...)
Affinity DataIC50:  870nMAssay Description:HEK293 engineering cells stably expressed with hERG potassium channel were used to test the compounds. Patch Clamp Detection: The cells were separate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594032((S)-(2-amino-7-(5-(3,4-diethoxyphenyl)-1,3,4-oxadi...)
Affinity DataIC50:  1.20E+3nMAssay Description:HEK293 engineering cells stably expressed with hERG potassium channel were used to test the compounds. Patch Clamp Detection: The cells were separate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594033((S)-5-(5-(7-amino-7-(hydroxymethyl)-5,6,7,8-tetrah...)
Affinity DataIC50:  7.80E+3nMAssay Description:HEK293 engineering cells stably expressed with hERG potassium channel were used to test the compounds. Patch Clamp Detection: The cells were separate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594032((S)-(2-amino-7-(5-(3,4-diethoxyphenyl)-1,3,4-oxadi...)
Affinity DataEC50: >1.00E+4nMAssay Description:The sample to be tested was dissolved in DMSO and diluted with detection buffer solution in 3-fold dilution. A reagent and a positive control were di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Beijing Foreland Pharma

US Patent
LigandPNGBDBM50158348((2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihy...)
Affinity DataEC50:  23nMAssay Description:The sample to be tested was dissolved in DMSO and diluted with detection buffer solution in 3-fold dilution. A reagent and a positive control were di...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Beijing Foreland Pharma

US Patent
LigandPNGBDBM594033((S)-5-(5-(7-amino-7-(hydroxymethyl)-5,6,7,8-tetrah...)
Affinity DataEC50:  250nMAssay Description:The sample to be tested was dissolved in DMSO and diluted with detection buffer solution in 3-fold dilution. A reagent and a positive control were di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent