Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with all data for entry = 50037011
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098853BDBM50098853(2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...)
Affinity DataKi:  1.12nMAssay Description:Inhibitory activity against canine skin chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098847BDBM50098847(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  3.68nMAssay Description:Inhibitory activity against canine skin chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098853BDBM50098853(2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...)
Affinity DataKi:  4.85nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098854BDBM50098854(2-{2-[2-(5-Amino-6-oxo-2-phenyl-6H-pyrimidin-1-yl)...)
Affinity DataKi:  5.57nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098841BDBM50098841(2-(2-{2-[5-Amino-2-(3-amino-phenyl)-6-oxo-6H-pyrim...)
Affinity DataKi:  5.60nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsin-C(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 87059BDBM87059(CHEMBL247767 | Chymostatin)
Affinity DataKi:  9.36nMAssay Description:inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 87059BDBM87059(CHEMBL247767 | Chymostatin)
Affinity DataKi:  13.1nMAssay Description:inhibitory activity was evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098849BDBM50098849(2-(2-{2-[5-Amino-2-(3-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  14.3nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098847BDBM50098847(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  22.6nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098842BDBM50098842(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  23.3nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098844BDBM50098844(2-(2-{2-[5-Amino-2-(3-chloro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  26.1nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098861BDBM50098861(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  30nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098862BDBM50098862(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  32.6nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMast cell protease 9(Mouse)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098847BDBM50098847(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  40.4nMAssay Description:Inhibitory activity against mouse peritoneal chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098864BDBM50098864(2-(2-{2-[5-Amino-2-(3-nitro-phenyl)-6-oxo-6H-pyrim...)
Affinity DataKi:  41.8nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098843BDBM50098843(2-{2-[2-(5-Amino-6-oxo-2-pyridin-4-yl-6H-pyrimidin...)
Affinity DataKi:  43.5nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098838BDBM50098838(2-{2-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl...)
Affinity DataKi:  44.2nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098839BDBM50098839(2-{2-[2-(5-Amino-6-oxo-2-pyridin-3-yl-6H-pyrimidin...)
Affinity DataKi:  45.1nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098854BDBM50098854(2-{2-[2-(5-Amino-6-oxo-2-phenyl-6H-pyrimidin-1-yl)...)
Affinity DataKi:  46.8nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098838BDBM50098838(2-{2-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl...)
Affinity DataKi:  47.7nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098856BDBM50098856(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  48nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098847BDBM50098847(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  52.9nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098858BDBM50098858(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  53.4nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098848BDBM50098848(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  56.3nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098842BDBM50098842(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  59.5nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098855BDBM50098855(N-[2-(5-Amino-benzooxazol-2-yl)-1-benzyl-2-oxo-eth...)
Affinity DataKi:  60nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098857BDBM50098857(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  60.5nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098857BDBM50098857(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  60.6nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMast cell protease 9(Mouse)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098853BDBM50098853(2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...)
Affinity DataKi:  63.9nMAssay Description:Inhibitory activity against mouse peritoneal chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098851BDBM50098851(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  65.1nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098862BDBM50098862(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  68.6nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098848BDBM50098848(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  71.3nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098856BDBM50098856(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  73.3nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098850BDBM50098850(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  76nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098839BDBM50098839(2-{2-[2-(5-Amino-6-oxo-2-pyridin-3-yl-6H-pyrimidin...)
Affinity DataKi:  77.4nMAssay Description:inhibitory activity was evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098852BDBM50098852(Hydrochloride salt of1-(2-Amino-3-methyl-butyryl)-...)
Affinity DataKi:  82.1nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Rat)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098853BDBM50098853(2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...)
Affinity DataKi:  86.6nMAssay Description:Inhibitory activity against rat peritoneal chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098851BDBM50098851(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  93.1nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098858BDBM50098858(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  94nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Rat)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098847BDBM50098847(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  103nMAssay Description:Inhibitory activity against rat peritoneal chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098860BDBM50098860(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  125nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098850BDBM50098850(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  133nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098845BDBM50098845(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  166nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098846BDBM50098846(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  174nMAssay Description:inhibitory activity was evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098845BDBM50098845(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  182nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymase(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098855BDBM50098855(N-[2-(5-Amino-benzooxazol-2-yl)-1-benzyl-2-oxo-eth...)
Affinity DataKi:  183nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098860BDBM50098860(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  229nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetCathepsin G(Human)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098853BDBM50098853(2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...)
Affinity DataKi:  379nMAssay Description:Inhibitory activity against human cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098843BDBM50098843(2-{2-[2-(5-Amino-6-oxo-2-pyridin-4-yl-6H-pyrimidin...)
Affinity DataKi:  467nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Welfide

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098861BDBM50098861(2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...)
Affinity DataKi:  477nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
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