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Found 15 Enz. Inhib. hit(s) with all data for entry = 50010944
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100403(CHEMBL423296 | {3-[4-(4-Bromo-phenyl)-thiazol-2-yl...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100395(CHEMBL28155 | [3-(4-Benzo[b]thiophen-3-yl-thiazol-...)
Affinity DataIC50:  1nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100400((4-Bromo-phenyl)-{5-methoxy-2-methyl-3-[4-(4-nitro...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100401((4-Bromo-phenyl)-{3-[4-(4-chloro-phenyl)-thiazol-2...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100404((4-Chloro-phenyl)-[5-methoxy-2-methyl-3-(4-naphtha...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100396(CHEMBL24407 | {3-[4-(3-Bromo-phenyl)-thiazol-2-ylm...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100399((4-Chloro-phenyl)-{3-[4-(4-fluoro-phenyl)-thiazol-...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100402((4-Chloro-phenyl)-{5-methoxy-2-methyl-3-[4-(4-nitr...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100397((4-Chloro-phenyl)-{3-[4-(4-chloro-phenyl)-thiazol-...)
Affinity DataIC50:  14nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100405((4-Bromo-phenyl)-{3-[4-(4-bromo-phenyl)-thiazol-2-...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  30nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100398(4-{2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-i...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100394(CHEMBL24687 | [3-(2-Amino-thiazol-4-ylmethyl)-5-me...)
Affinity DataIC50:  390nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibitory concentration of the compound against human recombinant Prostaglandin G/H synthase 1 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100394(CHEMBL24687 | [3-(2-Amino-thiazol-4-ylmethyl)-5-me...)
Affinity DataIC50:  1.55E+7nMAssay Description:Inhibitory concentration of the compound against human recombinant Prostaglandin G/H synthase 1 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed