Compile Data Set for Download or QSAR
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Found 22 Enz. Inhib. hit(s) with all data for entry = 50035135
TargetMu-type opioid receptor(GUINEA PIG)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  0.170nMAssay Description:Binding affinity towards Opioid receptor mu 1 of guinea pig brain membranes using radioligand 0.25 nM [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50001023((2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  0.180nMAssay Description:Binding affinity towards guinea pig Opioid receptor kappa 1 using radioligand [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  0.310nMAssay Description:Binding affinity towards guinea pig Opioid receptor kappa 1 using radioligand [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50001023((2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity towards guinea pig Opioid receptor mu 1 using radioligand [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101160(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataKi:  0.410nMAssay Description:Binding affinity towards guinea pig Opioid receptor mu 1 using radioligand [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101160(3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataKi:  0.530nMAssay Description:Binding affinity towards guinea pig Opioid receptor kappa 1 using radioligand [3H]U69,593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  0.880nMAssay Description:Binding affinity towards Opioid receptor mu 1 of guinea pig brain membranes using radioligand 0.25 nM [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50128411(3-desoxy-3-carboxamidonaltrexone | 4-cyclopropylme...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity towards Opioid receptor mu 1 of guinea pig brain membranes using radioligand 0.25 nM [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  11nMAssay Description:Binding affinity towards Opioid receptor delta 1 of guinea pig brain membranes using radioligand 0.2 nM [3H]NaltrindoleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50128411(3-desoxy-3-carboxamidonaltrexone | 4-cyclopropylme...)
Affinity DataKi:  22nMAssay Description:Binding affinity towards guinea pig Opioid receptor kappa 1 using radioligand [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  24nMAssay Description:Binding affinity towards guinea pig Opioid receptor kappa 1 using radioligand [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101158(14-hydroxy-4-methyl-(1S,5R,17R)-12-oxa-4-azapentac...)
Affinity DataKi:  34nMAssay Description:Binding affinity towards Opioid receptor mu 1 of guinea pig brain membranes using radioligand 0.25 nM [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50128411(3-desoxy-3-carboxamidonaltrexone | 4-cyclopropylme...)
Affinity DataKi:  110nMAssay Description:Binding affinity towards Opioid receptor delta 1 of guinea pig brain membranes using radioligand 0.2 nM [3H]NaltrindoleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  140nMAssay Description:Binding affinity towards Opioid receptor delta 1 of guinea pig brain membranes using radioligand 0.2 nM [3H]NaltrindoleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(GUINEA PIG)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101162(4,10N-dimethyl-14-hydroxy-(1S,5R,17R)-12-oxa-4-aza...)
Affinity DataKi:  440nMAssay Description:Binding affinity towards Opioid receptor mu 1 of guinea pig brain membranes using radioligand 0.25 nM [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101158(14-hydroxy-4-methyl-(1S,5R,17R)-12-oxa-4-azapentac...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity towards Opioid receptor delta 1 of guinea pig brain membranes using radioligand 0.2 nM [3H]NaltrindoleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101158(14-hydroxy-4-methyl-(1S,5R,17R)-12-oxa-4-azapentac...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity towards guinea pig Opioid receptor kappa 1 using radioligand [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101159(4,10N,10N-trimethyl-14-hydroxy-(1S,5R,17R)-12-oxa-...)
Affinity DataKi:  5.80E+3nMAssay Description:Binding affinity towards Opioid receptor mu 1 of guinea pig brain membranes using radioligand 0.25 nM [3H]DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101162(4,10N-dimethyl-14-hydroxy-(1S,5R,17R)-12-oxa-4-aza...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards guinea pig Opioid receptor kappa 1 using radioligand [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101162(4,10N-dimethyl-14-hydroxy-(1S,5R,17R)-12-oxa-4-aza...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards Opioid receptor delta 1 of guinea pig brain membranes using radioligand 0.2 nM [3H]NaltrindoleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101159(4,10N,10N-trimethyl-14-hydroxy-(1S,5R,17R)-12-oxa-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards guinea pig Opioid receptor kappa 1 using radioligand [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50101159(4,10N,10N-trimethyl-14-hydroxy-(1S,5R,17R)-12-oxa-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards Opioid receptor delta 1 of guinea pig brain membranes using radioligand 0.2 nM [3H]NaltrindoleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed