Affinity DataKi: 2.20nMAssay Description:Binding against the partially purified human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibitory activity against the partially purified human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibitory activity against the partially purified human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of chemotactic protein to CCR5More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of p53 binding to Glutathione S-transferase 2 (hdm2-GST)More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of chemotactic protein to CCR2bMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2-domain bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Antagonist activity against the C5a receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of Src protein tryrosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of NGF-stimulated Trk AMore data for this Ligand-Target Pair
TargetTumor necrosis factor receptor superfamily member 16(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.72E+3nMAssay Description:Competitive binding against Nerve growth factor to p75-NGF receptor in PC12 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of binding to Src SH2 domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5.88E+3nMAssay Description:Inhibition of NGF-stimulated Trk AMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Inhibition of calcium release in Jurkat cells after T-cell receptor cross linking antibody treatmentMore data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity for p56 lck kinaseMore data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Inhibition of p56 Lck SH2 domain binding to pYEEIMore data for this Ligand-Target Pair