Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50022630
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 100nMAssay Description:Inhibition of His6-tagged recombinant human CDK2/cyclin E expressed in baculovirus infected Sf21 cells using histone H1 as substrate in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50056163((S)-2-(6-Benzylamino-9-isopropyl-9H-purin-2-ylamin...)
Affinity DataIC50: 240nMAssay Description:Inhibition of His6-tagged recombinant human CDK2/cyclin E expressed in baculovirus infected Sf21 cells using histone H1 as substrate in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 490nMAssay Description:Inhibition of His6-tagged recombinant human CDK7/cyclin H expressed in baculovirus infected Sf21 cells in presence of gamma-32P-ATP by scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of human ERK-2 using myelin as substrate in presence of gamma-32P-ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of His6-tagged recombinant human CDK1/cyclin B expressed in baculovirus infected Sf21 cells by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of His6-tagged recombinant human CDK4/cyclin D1 expressed in baculovirus infected Sf21 cells using GST-retinoblastoma(773-928) as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human SAPK2A using myelin as substrate in presence of gamma-32P-ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PKAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PKCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed