Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 725
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5459BDBM5459(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-{...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5456BDBM5456(N-(3-ethynylphenyl)-6-{4-[(2-methanesulfonylethyl)...)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5460BDBM5460(N-{1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl}-6-{...)
Affinity DataIC50: 19nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5457BDBM5457(N-(3-chloro-4-fluorophenyl)-6-{4-[(2-methanesulfon...)
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5460BDBM5460(N-{1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl}-6-{...)
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5459BDBM5459(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-{...)
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5451BDBM5451(N-[4-(benzyloxy)phenyl]-6-methoxyquinazolin-4-amin...)
Affinity DataIC50: 68nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5450BDBM5450(N-[4-(benzyloxy)phenyl]-6-{4-[(2-methanesulfonylet...)
Affinity DataIC50: 74nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5455BDBM5455(N-{4-[(4-{[4-(benzyloxy)phenyl]amino}quinazolin-6-...)
Affinity DataIC50: 74nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5452BDBM5452(N-[4-(benzyloxy)phenyl]-6-(prop-2-en-1-yloxy)quina...)
Affinity DataIC50: 79nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5458BDBM5458(N-[4-(benzenesulfonyl)phenyl]-6-{4-[(2-methanesulf...)
Affinity DataIC50: 93nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5450BDBM5450(N-[4-(benzyloxy)phenyl]-6-{4-[(2-methanesulfonylet...)
Affinity DataIC50: 95nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5448BDBM5448(4-{[4-(benzyloxy)phenyl]amino}quinazolin-6-ol | 4-...)
Affinity DataIC50: 98nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5453BDBM5453(N-[4-(benzyloxy)phenyl]-6-{3-[(2-methanesulfonylet...)
Affinity DataIC50: 104nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5455BDBM5455(N-{4-[(4-{[4-(benzyloxy)phenyl]amino}quinazolin-6-...)
Affinity DataIC50: 117nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5458BDBM5458(N-[4-(benzenesulfonyl)phenyl]-6-{4-[(2-methanesulf...)
Affinity DataIC50: 147nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5457BDBM5457(N-(3-chloro-4-fluorophenyl)-6-{4-[(2-methanesulfon...)
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5453BDBM5453(N-[4-(benzyloxy)phenyl]-6-{3-[(2-methanesulfonylet...)
Affinity DataIC50: 234nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5456BDBM5456(N-(3-ethynylphenyl)-6-{4-[(2-methanesulfonylethyl)...)
Affinity DataIC50: 234nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5449BDBM5449(N-{4-[(4-{[4-(benzyloxy)phenyl]amino}quinazolin-6-...)
Affinity DataIC50: 263nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5448BDBM5448(4-{[4-(benzyloxy)phenyl]amino}quinazolin-6-ol | 4-...)
Affinity DataIC50: 263nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5451BDBM5451(N-[4-(benzyloxy)phenyl]-6-methoxyquinazolin-4-amin...)
Affinity DataIC50: 309nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5452BDBM5452(N-[4-(benzyloxy)phenyl]-6-(prop-2-en-1-yloxy)quina...)
Affinity DataIC50: 347nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5454BDBM5454(N-[4-(benzyloxy)phenyl]-6-{3-[(2-methanesulfonylet...)
Affinity DataIC50: 830nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5449BDBM5449(N-{4-[(4-{[4-(benzyloxy)phenyl]amino}quinazolin-6-...)
Affinity DataIC50: 977nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

LigandChemical structure of BindingDB Monomer ID 5454BDBM5454(N-[4-(benzyloxy)phenyl]-6-{3-[(2-methanesulfonylet...)
Affinity DataIC50: 1.78E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic reactions were initiated by adding kinase to the reaction mixture containing ATP, [gamma-33P] ATP, peptide substrate and test inhibitor com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2005
Entry Details Article
PubMed