Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50000095
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001265(CHEMBL116733 | 3-(4-Amino-phenyl)-5,7-dichloro-4-h...)
Affinity DataKi:  18nMAssay Description:Ability to displace strychnine-insensitive [3H]glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001266(CHEMBL50267 | 5,7-dichlorokynurenic acid | 5,7-Dic...)
Affinity DataKi:  40nMAssay Description:Ability to displace strychnine-insensitive [3H]glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001265(CHEMBL116733 | 3-(4-Amino-phenyl)-5,7-dichloro-4-h...)
Affinity DataIC50: 210nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001264(CHEMBL419940 | 5,7-Dichloro-4-hydroxy-3-p-tolyl-1H...)
Affinity DataKi:  300nMAssay Description:Ability to displace strychnine-insensitive [3H]glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001264(CHEMBL419940 | 5,7-Dichloro-4-hydroxy-3-p-tolyl-1H...)
Affinity DataIC50: 550nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001266(CHEMBL50267 | 5,7-dichlorokynurenic acid | 5,7-Dic...)
Affinity DataIC50: 860nMAssay Description:Ability to displace strychnine-insensitive [3H]glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001268(CHEMBL116814 | 5,7-Dichloro-4-hydroxy-3-(4-nitro-p...)
Affinity DataKi:  860nMAssay Description:Ability to displace strychnine-insensitive [3H]glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001260(4-hydroxy-3-phenylquinolin-2(1H)-one | 3-phenyl-4-...)
Affinity DataKi:  4.50E+3nMAssay Description:Ability to displace strychnine-insensitive [3H]glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM81975(4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...)
Affinity DataKi:  5.40E+3nMAssay Description:Ability to displace strychnine-insensitive [3H]glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001260(4-hydroxy-3-phenylquinolin-2(1H)-one | 3-phenyl-4-...)
Affinity DataIC50: 7.29E+3nMAssay Description:Ability to displace strychnine-insensitive [3H]glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM81975(4-hydroxyquinoline-2-carboxylic acid | NSC_5280455...)
Affinity DataIC50: 4.02E+4nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed