Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50000219
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003059(CHEMBL123231 | 2-[4-(7-Amino-9-oxo-1,3,3a,4,5,8,9,...)
Affinity DataIC50: 5.00E+3nMAssay Description:Compound was evaluated for the inhibition of Lactobacillus casei DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003058(CHEMBL331208 | 2-[4-(7-Amino-9-oxo-8,9-dihydro-2,5...)
Affinity DataIC50: 1.70E+4nMAssay Description:Compound was evaluated for the inhibition of Aminoimidazole carboxamide ribonucleotide formyl transferase (AICAR) with (6R) tetrahydrofolate as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003059(CHEMBL123231 | 2-[4-(7-Amino-9-oxo-1,3,3a,4,5,8,9,...)
Affinity DataIC50: 4.00E+4nMAssay Description:Compound was evaluated for the inhibition of Lactobacillus casei DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003059(CHEMBL123231 | 2-[4-(7-Amino-9-oxo-1,3,3a,4,5,8,9,...)
Affinity DataIC50: 4.00E+4nMAssay Description:Compound was evaluated for the inhibition of Aminoimidazole carboxamide ribonucleotide formyl transferase (AICAR) with (6R) tetrahydrofolate as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003059(CHEMBL123231 | 2-[4-(7-Amino-9-oxo-1,3,3a,4,5,8,9,...)
Affinity DataIC50: 4.00E+4nMAssay Description:Compound was evaluated for the inhibition of recombinant human thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003059(CHEMBL123231 | 2-[4-(7-Amino-9-oxo-1,3,3a,4,5,8,9,...)
Affinity DataIC50: 4.00E+4nMAssay Description:Compound was evaluated for the inhibition of Glycinamide ribonucleotide formyl transferase (GAR) with formyl (6R) tetrahydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003058(CHEMBL331208 | 2-[4-(7-Amino-9-oxo-8,9-dihydro-2,5...)
Affinity DataIC50: 8.00E+4nMAssay Description:Compound was evaluated for the inhibition of recombinant human Dihydrofolate reductase (DHFR); no inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003057(CHEMBL122959 | 7-Amino-1,2,3-trimethyl-2,8-dihydro...)
Affinity DataIC50: 9.50E+4nMAssay Description:Compound was evaluated for the inhibition of Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003058(CHEMBL331208 | 2-[4-(7-Amino-9-oxo-8,9-dihydro-2,5...)
Affinity DataIC50: 9.50E+4nMAssay Description:Compound was evaluated for the inhibition of Glycinamide ribonucleotide formyl transferase (GAR) with formyl (6R) tetrahydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003057(CHEMBL122959 | 7-Amino-1,2,3-trimethyl-2,8-dihydro...)
Affinity DataIC50: 9.50E+4nMAssay Description:Compound was evaluated for the inhibition of recombinant human Dihydrofolate reductase (DHFR); no inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003057(CHEMBL122959 | 7-Amino-1,2,3-trimethyl-2,8-dihydro...)
Affinity DataIC50: 9.50E+4nMAssay Description:Compound was evaluated for the inhibition of Aminoimidazole carboxamide ribonucleotide formyl transferase (AICAR) with (6R) tetrahydrofolate as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003057(CHEMBL122959 | 7-Amino-1,2,3-trimethyl-2,8-dihydro...)
Affinity DataIC50: 9.50E+4nMAssay Description:Compound was evaluated for the inhibition of Glycinamide ribonucleotide formyl transferase (GAR) with formyl (6R) tetrahydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50003058(CHEMBL331208 | 2-[4-(7-Amino-9-oxo-8,9-dihydro-2,5...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for the inhibition of Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed