Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 1722
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13599BDBM13599(CHEMBL269166 | 3-{4-[2-(1H-1,2,3-benzotriazol-1-yl...)
Affinity DataIC50: 3nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13599BDBM13599(CHEMBL269166 | 3-{4-[2-(1H-1,2,3-benzotriazol-1-yl...)
Affinity DataIC50: 3nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13604BDBM13604(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)
Affinity DataIC50: 5nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13601BDBM13601(5-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)
Affinity DataIC50: 6nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13603BDBM13603(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)
Affinity DataIC50: 6nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13600BDBM13600(5-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)
Affinity DataIC50: 10nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13605BDBM13605(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)
Affinity DataIC50: 11nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13595BDBM13595(CHEMBL276647 | ({4-[2-(1H-1,2,3-benzotriazol-1-yl)...)
Affinity DataIC50: 11nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13602BDBM13602(CHEMBL268526 | 6-{4-[2-(1H-1,2,3-benzotriazol-1-yl...)
Affinity DataIC50: 12nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13596BDBM13596(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluoro...)
Affinity DataIC50: 13nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13595BDBM13595(CHEMBL276647 | ({4-[2-(1H-1,2,3-benzotriazol-1-yl)...)
Affinity DataIC50: 16nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13603BDBM13603(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)
Affinity DataIC50: 17nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13601BDBM13601(5-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)
Affinity DataIC50: 20nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13602BDBM13602(CHEMBL268526 | 6-{4-[2-(1H-1,2,3-benzotriazol-1-yl...)
Affinity DataIC50: 20nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13605BDBM13605(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)
Affinity DataIC50: 21nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13597BDBM13597(({4-[(4E)-2-(1,3-benzothiazol-2-yl)-2-(1H-1,2,3-be...)
Affinity DataIC50: 23nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13598BDBM13598(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-2-phenyl-3-(4-...)
Affinity DataIC50: 24nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13600BDBM13600(5-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)
Affinity DataIC50: 31nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13604BDBM13604(6-{4-[2-(1H-1,2,3-benzotriazol-1-yl)-3-{4-[difluor...)
Affinity DataIC50: 36nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13598BDBM13598(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-2-phenyl-3-(4-...)
Affinity DataIC50: 38nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Human)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 13593BDBM13593(({4-[(2R)-2-(1H-1,2,3-benzotriazol-1-yl)-2-phenyle...)
Affinity DataIC50: 8.04E+3nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2007
Entry Details Article
PubMed