Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50037318
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229786BDBM50229786(5-[2,3-Dichloro-4-(5-{1-[2-((R)-2-guanidino-4-meth...)
Affinity DataEC50:  3nMAssay Description:Effective concentration required against phosphorylation of Mammary gland factor/STAT5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50229786BDBM50229786(5-[2,3-Dichloro-4-(5-{1-[2-((R)-2-guanidino-4-meth...)
Affinity DataIC50: 60nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147987BDBM50147987(4-[2,3-Dichloro-4-(5-{1-[2-((R)-2-guanidino-4-meth...)
Affinity DataIC50: 200nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148004BDBM50148004(3-[2,3-Dichloro-4-(5-{1-[2-((R)-2-guanidino-4-meth...)
Affinity DataIC50: 400nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147979BDBM50147979({4-[2,3-Dichloro-4-(5-{1-[2-((R)-2-guanidino-4-met...)
Affinity DataIC50: 600nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148000BDBM50148000(2-Guanidino-4-methyl-pentanoic acid (2-{4-[5-(2,3-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148001BDBM50148001(2-Guanidino-4-methyl-pentanoic acid (2-{4-[5-(2,3-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147974BDBM50147974(2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of mouse Interleukin-2 receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147970BDBM50147970(2-Guanidino-4-methyl-pentanoic acid (2-{4-[5-(2,3-...)
Affinity DataIC50: 8.10E+3nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147999BDBM50147999((S)-2-[2-((S)-2-Guanidino-3,3-dimethyl-butyrylamin...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of mouse interleukin-2 alpha receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148008BDBM50148008(2-(R)-Cyclohexyl-N-(2-{4-[5-(2,3-dichloro-phenyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147973BDBM50147973(2-(R)-Cyclohexyl-N-(2-{4-[5-(2,4-dichloro-phenyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147985BDBM50147985((S)-2-[2-((R)-2-Cyclohexyl-2-guanidino-acetylamino...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse interleukin-2 alpha receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147982BDBM50147982(2-Cyclohexyl-N-(2-{4-[5-(2,3-dichloro-phenyl)-2-me...)
Affinity DataIC50: 2.00E+4nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370390BDBM50370390(CHEMBL1790808)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of mouse interleukin-2 alpha receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147975BDBM50147975(N-(2-{4-[5-(2-Chloro-4-hydroxy-phenyl)-2H-pyrazol-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147984BDBM50147984(2-Guanidino-4-methyl-pentanoic acid (2-{4-[5-(4-be...)
Affinity DataIC50: 3.50E+4nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148006BDBM50148006((S)-2-[2-((R)-3-Cyclohexyl-2-guanidino-propionylam...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of mouse interleukin-2 alpha receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147989BDBM50147989(N-(2-{4-[5-(2-Chloro-phenyl)-2H-pyrazol-3-yl]-pipe...)
Affinity DataIC50: 4.00E+4nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148003BDBM50148003(4-[2,3-Dichloro-4-(5-{1-[2-((R)-2-guanidino-4-meth...)
Affinity DataIC50: 4.00E+4nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148002BDBM50148002(N-(2-{4-[5-(2-Chloro-4-methoxy-phenyl)-2H-pyrazol-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147998BDBM50147998(2-(R)-Cyclohexyl-2-guanidino-N-{2-oxo-2-[4-(5-o-to...)
Affinity DataIC50: 5.00E+4nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147997BDBM50147997(2-Cyclohexyl-N-(2-{4-[5-(2,3-dichloro-phenyl)-1-me...)
Affinity DataIC50: 5.00E+4nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147995BDBM50147995((S)-2-[2-((S)-2-Guanidino-3-methyl-butyrylamino)-a...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of mouse interleukin-2 alpha receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147974BDBM50147974(2-[3-METHYL-4-(N-METHYL-GUANIDINO)-BUTYRYLAMINO]-3...)
Affinity DataEC50:  1.00E+5nMAssay Description:Effective concentration required against phosphorylation of Mammary gland factor/STAT5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147992BDBM50147992(2-(R)-Cyclohexyl-N-(2-{4-[5-(3,4-dichloro-phenyl)-...)
Affinity DataIC50: 1.10E+5nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147976BDBM50147976(2-(R)-Cyclohexyl-2-guanidino-N-{2-oxo-2-[4-(5-phen...)
Affinity DataIC50: 1.20E+5nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147994BDBM50147994(N-(2-{4-[5-(3-Chloro-phenyl)-2H-pyrazol-3-yl]-pipe...)
Affinity DataIC50: 1.30E+5nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147972BDBM50147972(2-(R)-Cyclohexyl-N-(2-{4-[5-(2,3-dimethyl-phenyl)-...)
Affinity DataIC50: 1.30E+5nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147993BDBM50147993(2-Cyclohexyl-N-{2-[4-(2',4'-dichloro-biphenyl-3-yl...)
Affinity DataIC50: 1.50E+5nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147990BDBM50147990(2-(R)-Cyclohexyl-2-guanidino-N-{2-oxo-2-[4-(5-m-to...)
Affinity DataIC50: 1.50E+5nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147991BDBM50147991((S)-2-[2-((S)-2-Guanidino-propionylamino)-acetylam...)
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibition of mouse interleukin-2 alpha receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147983BDBM50147983(2-Cyclohexyl-N-(2-{4-[5-(2,3-dichloro-phenyl)-4-me...)
Affinity DataIC50: 4.00E+5nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147977BDBM50147977(2-Cyclohexyl-N-(2-{4-[3-(2,4-dichloro-phenyl)-[1,2...)
Affinity DataIC50: 5.00E+5nMAssay Description:Concentration required to inhibit mouse interleukin-2 alpha receptor was determined by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147980BDBM50147980((S)-2-{2-[(1-Carbamimidoyl-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 7.20E+5nMAssay Description:Inhibition of mouse interleukin-2 alpha receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147996BDBM50147996(2-[(S)-2-(4-Carbamoyl-2-guanidino-butyrylamino)-ac...)
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of mouse interleukin-2 alpha receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147971BDBM50147971((S)-2-{2-[(1-Carbamimidoyl-pyrrolidine-2-carbonyl)...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mouse interleukin-2 alpha receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148005BDBM50148005((S)-2-{2-[2-(N-Methyl-guanidino)-acetylamino]-acet...)
Affinity DataIC50: 1.20E+6nMAssay Description:Inhibition of mouse interleukin-2 alpha receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147978BDBM50147978((S)-2-[2-((R)-2-Guanidino-3-methyl-butyrylamino)-a...)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of mouse interleukin-2 alpha receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50147988BDBM50147988((S)-2-[2-(2-Guanidino-acetylamino)-acetylamino]-3-...)
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of mouse interleukin-2 alpha receptor by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetInterleukin-2 receptor subunit alpha(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50148007BDBM50148007((S)-2-(2-Methoxy-acetylamino)-3-(4-phenylethynyl-p...)
Affinity DataIC50: 2.20E+6nMAssay Description:Inhibition of mouse Interleukin-2 receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed