Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with all data for entry = 50036038
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataIC50:  40nMAssay Description:Concentration required to inhibit HIV reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50132287(1-((2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydro...)
Affinity DataIC50: <50nMAssay Description:Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50018445(1-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)...)
Affinity DataIC50: <50nMAssay Description:Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50004773(1-(4,4-Difluoro-5-hydroxymethyl-tetrahydro-furan-2...)
Affinity DataIC50:  8.80E+3nMAssay Description:Concentration required to inhibit HIV reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed