Compile Data Set for Download or QSAR
Report error Found 134 Enz. Inhib. hit(s) with all data for entry = 1068
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8611BDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 1nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8586BDBM8586(3-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8608BDBM8608(3-{[(1E)-4-chloro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 9nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8611BDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 10nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8587BDBM8587(3-{[(1Z)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8581BDBM8581(3-[(1E)-2,3-dihydro-1H-inden-1-ylidenemethyl]pyrid...)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8607BDBM8607(3-{[(1E)-4-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 21nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8584BDBM8584(3-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidenemeth...)
Affinity DataIC50: 22nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8588BDBM8588(3-{[(1E)-5-chloro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8640BDBM8640(5-{[(1Z)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 26nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8594BDBM8594(3-{[(1Z)-5-methoxy-2,3-dihydro-1H-inden-1-ylidene]...)
Affinity DataIC50: 26nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8600BDBM8600(3-{[(1E)-7-methoxy-2,3-dihydro-1H-inden-1-ylidene]...)
Affinity DataIC50: 27nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8631BDBM8631(5-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 27nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8611BDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 30nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8611BDBM8611(CHEMBL468419 | 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridi...)
Affinity DataIC50: 30nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8609BDBM8609(3-{[(1Z)-4-chloro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 31nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8615BDBM8615(4-{[(1Z)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 34nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8593BDBM8593(3-{[(1E)-5-methoxy-2,3-dihydro-1H-inden-1-ylidene]...)
Affinity DataIC50: 34nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8590BDBM8590(3-{[(1E)-5-bromo-2,3-dihydro-1H-inden-1-ylidene]me...)
Affinity DataIC50: 37nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8595BDBM8595(3-{[(1E)-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-...)
Affinity DataIC50: 57nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8639BDBM8639(5-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 58nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8589BDBM8589(3-{[(1Z)-5-chloro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 73nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8597BDBM8597(3-{[(1E)-5-ethoxy-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 79nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8610BDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataIC50: 81nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8583BDBM8583(3-[(Z)-2,3-Dihydro-1H-inden-1-ylidenemethyl]pyridi...)
Affinity DataIC50: 87nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8628BDBM8628(4-{[(1E)-6,7-dimethoxy-1,2,3,4-tetrahydronaphthale...)
Affinity DataIC50: 90nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8583BDBM8583(3-[(Z)-2,3-Dihydro-1H-inden-1-ylidenemethyl]pyridi...)
Affinity DataIC50: 92nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8645BDBM8645(4-(2,2-diphenylethenyl)pyridine | 4-Pyridylmethyle...)
Affinity DataIC50: 100nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8599BDBM8599(3-{[(1E)-4-methyl-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 108nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8587BDBM8587(3-{[(1Z)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 125nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8608BDBM8608(3-{[(1E)-4-chloro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 130nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8585BDBM8585(3-[(Z)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]p...)
Affinity DataIC50: 141nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8613BDBM8613(4-[(E)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]p...)
Affinity DataIC50: 143nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8641BDBM8641(3-{1-[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene...)
Affinity DataIC50: 159nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8591BDBM8591(3-{[(1Z)-5-bromo-2,3-dihydro-1H-inden-1-ylidene]me...)
Affinity DataIC50: 171nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8617BDBM8617(3-{[(1Z)-4-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 180nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8596BDBM8596(3-{[(1Z)-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-...)
Affinity DataIC50: 206nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8610BDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataIC50: 224nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8609BDBM8609(3-{[(1Z)-4-chloro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 230nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8618BDBM8618(4-{[(1E)-5-chloro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 243nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8598BDBM8598(3-{[(1Z)-5-ethoxy-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 248nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8615BDBM8615(4-{[(1Z)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 257nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8589BDBM8589(3-{[(1Z)-5-chloro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 270nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8626BDBM8626(4-{[(1E)-6-methoxy-2,3-dihydro-1H-inden-1-ylidene]...)
Affinity DataIC50: 280nMAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8613BDBM8613(4-[(E)-3,4-Dihydronaphthalen-1(2H)-ylidenemethyl]p...)
Affinity DataIC50: 282nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8619BDBM8619(4-{[(1Z)-5-chloro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 301nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8608BDBM8608(3-{[(1E)-4-chloro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 304nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8586BDBM8586(3-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 311nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8591BDBM8591(3-{[(1Z)-5-bromo-2,3-dihydro-1H-inden-1-ylidene]me...)
Affinity DataIC50: 320nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandChemical structure of BindingDB Monomer ID 8640BDBM8640(5-{[(1Z)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 374nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2006
Entry Details Article
PubMed
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