Compile Data Set for Download or QSAR
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Found 22 Enz. Inhib. hit(s) with all data for entry = 50015929
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161093((R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthale...)
Affinity DataIC50:  43nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162536(6-Fluoro-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-hydrox...)
Affinity DataIC50:  190nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162537(6-Fluoro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...)
Affinity DataIC50:  210nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162547(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50:  250nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162538(2-(2-Hydroxy-phenyl)-5-methyl-3-phenethyl-3H-quina...)
Affinity DataIC50:  250nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162553(6-Chloro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162554(2-(2-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162539(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50:  520nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162552(7-Fluoro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162545(2-(2-Hydroxy-phenyl)-8-methyl-3-phenethyl-3H-quina...)
Affinity DataIC50:  700nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162555(3-[2-(3-Chloro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50:  800nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162549(7-Chloro-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-hydrox...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162546(2-(2,5-Dihydroxy-phenyl)-3-phenethyl-3H-quinazolin...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162535(2-(3-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162542(2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one | CHE...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162540(3-Phenethyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162548(2-(4-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162551(2-(2-Fluoro-phenyl)-3-phenethyl-3H-quinazolin-4-on...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162550(2-(3-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162544(2-(2-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162541(2-(4-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162543(2-(3-Fluoro-phenyl)-3-phenethyl-3H-quinazolin-4-on...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed