Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50015952
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162822BDBM50162822(1-(1-{3-[3-(3,4-Dichloro-phenyl)-5-methanesulfonyl...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152992BDBM50152992(1-[1-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazi...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152989BDBM50152989(Carbamic acid 2-[5-carbamoyl-3-(4-iodo-phenyl)-4,5...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162858BDBM50162858(6-Chloro-1-(1-{3-[5-methanesulfonyl-3-(4-trifluoro...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162843BDBM50162843(3-(1-{2-Hydroxy-3-[5-methanesulfonyl-3-(4-trifluor...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162828BDBM50162828(1-(1-(3-(3-(3,4-dichlorophenyl)-5-(methylsulfonyl)...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162853BDBM50162853(6-Chloro-1-(1-{3-[3-(4-chloro-3-methyl-phenyl)-5-m...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162824BDBM50162824(1-(1-{3-[3-(4-Bromo-phenyl)-5-methanesulfonyl-4,5,...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162838BDBM50162838(1-(1-{3-[5-Methanesulfonyl-3-(4-trifluoromethyl-ph...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162847BDBM50162847(1-(1-{2-Hydroxy-3-[5-methanesulfonyl-3-(4-trifluor...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152985BDBM50152985(1-{3-[4-(2-Cyano-phenyl)-piperazin-1-yl]-2-hydroxy...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162857BDBM50162857(1-(1-{3-[3-(4-Bromo-phenyl)-5-methanesulfonyl-4,5,...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162839BDBM50162839(1-(1-{3-[3-(4-Chloro-3-methyl-phenyl)-5-methanesul...)
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162832BDBM50162832(6-Chloro-1-(1-{2-hydroxy-3-[5-methanesulfonyl-3-(4...)
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162848BDBM50162848(5-Chloro-3-(1-{2-hydroxy-3-[5-methanesulfonyl-3-(4...)
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162834BDBM50162834(1-(1-{3-[5-Acetyl-3-(4-bromo-phenyl)-4,5,6,7-tetra...)
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162823BDBM50162823(1-(1-{3-[5-Acetyl-3-(4-chloro-3-methyl-phenyl)-4,5...)
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162826BDBM50162826(1-(1-{3-[5-Acetyl-3-(4-bromo-phenyl)-4,5,6,7-tetra...)
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162842BDBM50162842(1-(1-{3-[5-Acetyl-3-(4-trifluoromethyl-phenyl)-4,5...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162825BDBM50162825(1-(1-{3-[5-Acetyl-3-(4-chloro-3-methyl-phenyl)-4,5...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162851BDBM50162851([3-(1-{3-[5-Methanesulfonyl-3-(4-trifluoromethyl-p...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162844BDBM50162844(1-(1-{3-[5-Acetyl-3-(4-chloro-3-methyl-phenyl)-4,5...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162827BDBM50162827(5-chloro-1-methyl-3-(1-(3-(5-(methylsulfonyl)-3-(4...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162835BDBM50162835(1-(1-{3-[5-Acetyl-3-(4-trifluoromethyl-phenyl)-4,5...)
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162829BDBM50162829(1-(1-{3-[5-Acetyl-3-(4-bromo-phenyl)-4,5,6,7-tetra...)
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50152988BDBM50152988(2-(4-{3-[5-Acetyl-3-(4-iodo-phenyl)-4,5,6,7-tetrah...)
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162821BDBM50162821(1-(1-{3-[5-Acetyl-3-(4-iodo-phenyl)-4,5,6,7-tetrah...)
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162837BDBM50162837(1-(1-{3-[5-Acetyl-3-(4-bromo-phenyl)-4,5,6,7-tetra...)
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162831BDBM50162831(1-(1-{3-[5-Acetyl-3-(4-trifluoromethoxy-phenyl)-4,...)
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162845BDBM50162845(1-(1-{3-[5-Acetyl-3-(4-chloro-3-methyl-phenyl)-4,5...)
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162836BDBM50162836(1-(1-{3-[3-(4-Bromo-phenyl)-5-methanesulfonyl-4,5,...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162820BDBM50162820(1-(1-{3-[5-Acetyl-3-(4-bromo-phenyl)-4,5,6,7-tetra...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162846BDBM50162846(1-(1-{3-[5-Acetyl-3-(4-chloro-3-methyl-phenyl)-4,5...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162856BDBM50162856(5-Chloro-3-(1-{3-[3-(3,4-dichloro-phenyl)-5-methan...)
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162854BDBM50162854(1-(1-{(R)-3-[5-Acetyl-3-(4-trifluoromethyl-phenyl)...)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162833BDBM50162833(1-(1-{(S)-3-[5-Acetyl-3-(4-chloro-3-methyl-phenyl)...)
Affinity DataIC50: 190nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162841BDBM50162841(1-(1-{(S)-3-[5-Acetyl-3-(4-trifluoromethyl-phenyl)...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162855BDBM50162855(1-(1-{3-[5-Acetyl-3-(4-bromo-phenyl)-4,5,6,7-tetra...)
Affinity DataIC50: 210nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162850BDBM50162850(1-(1-{3-[5-Acetyl-3-(4-iodo-phenyl)-4,5,6,7-tetrah...)
Affinity DataIC50: 230nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162852BDBM50162852(1-(1-{3-[5-Acetyl-3-(4-chloro-3-methyl-phenyl)-4,5...)
Affinity DataIC50: 310nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162830BDBM50162830(1-(1-{(R)-3-[5-Acetyl-3-(4-chloro-3-methyl-phenyl)...)
Affinity DataIC50: 350nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162849BDBM50162849(1-(1-{3-[5-Acetyl-3-(4-chloro-phenyl)-4,5,6,7-tetr...)
Affinity DataIC50: 460nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50162840BDBM50162840(1-(1-{3-[5-Acetyl-3-(4-chloro-3-methyl-phenyl)-4,5...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed