Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50037572
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164606((2R)-3'-(5-bromothien-2-yl)-2'H-spiro[4-azabicyclo...)
Affinity DataKi:  4nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164618((2R)-3'-(5-chlorothien-2-yl)-2'H-spiro[4-azabicycl...)
Affinity DataKi:  9nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164607((2R)-3'-(5-methylthien-2-yl)-2'H-spiro[4-azabicycl...)
Affinity DataKi:  12nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149146((S)-3-(Benzo[b]thiophen-2-ylmethoxy)-1-aza-bicyclo...)
Affinity DataKi:  13nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164611((2R)-3'-(5-ethylthien-2-yl)-2'H-spiro[4-azabicyclo...)
Affinity DataKi:  21nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164621((2R)-3'-(2-naphthyl)-2'H-spiro[4-azabicyclo[2.2.2]...)
Affinity DataKi:  31nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50149147(2-(1-Aza-bicyclo[2.2.2]oct-3-yl)-1-benzo[b]thiophe...)
Affinity DataKi:  65nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164627((2R)-3'-(5-isopropylthien-2-yl)-2'H-spiro[4-azabic...)
Affinity DataKi:  65nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164622((2R)-3'-(1-benzothien-2-yl)-2'H-spiro[4-azabicyclo...)
Affinity DataKi:  75nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164612((2R)-3'-thien-2-yl-2'H-spiro[4-azabicyclo[2.2.2]oc...)
Affinity DataKi:  80nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164619(5-[(2R)-2'-oxo-3'H-spiro[4-azabicyclo[2.2.2]octane...)
Affinity DataKi:  85nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164628((2R)-3'-[5-(1-hydroxyethyl)thien-2-yl]-2'H-spiro[4...)
Affinity DataKi:  145nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164614((2R)-3'-(5-acetylthien-2-yl)-2'H-spiro[4-azabicycl...)
Affinity DataKi:  190nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164608((2S)-3'-(2-naphthyl)-2'H-spiro[4-azabicyclo[2.2.2]...)
Affinity DataKi:  205nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50061564(3-[1-(2,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-3,4,...)
Affinity DataKi:  220nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50093255(2'H-spiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxaz...)
Affinity DataKi:  340nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164629((2R)-3'-(1-benzofuran-2-yl)-2'H-spiro[4-azabicyclo...)
Affinity DataKi:  370nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164615((2R)-3'-(1,3-benzothiazol-2-yl)-2'H-spiro[4-azabic...)
Affinity DataKi:  430nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164624((2R)-3'-quinolin-2-yl-2'H-spiro[4-azabicyclo[2.2.2...)
Affinity DataKi:  450nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164617((2R)-3'-pyridin-2-yl-2'H-spiro[4-azabicyclo[2.2.2]...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164616((2R)-3'-(1,3-benzoxazol-2-yl)-2'H-spiro[4-azabicyc...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164626((2R)-3'-thien-3-yl-2'H-spiro[4-azabicyclo[2.2.2]oc...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164625((2R)-3'-(4,5-dimethylthien-2-yl)-2'H-spiro[4-azabi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164610((2S)-3'-(1-benzothien-2-yl)-2'H-spiro[4-azabicyclo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164609(3'-phenyl-2'H-spiro[4-azabicyclo[2.2.2]octane-2,5'...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164623((2R)-3'-(3-methylthien-2-yl)-2'H-spiro[4-azabicycl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50164620((2R)-3'-(4-methylthien-2-yl)-2'H-spiro[4-azabicycl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [125I]alpha-bungarotoxin binding to rat nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed