Compile Data Set for Download or QSAR
Report error Found 136 Enz. Inhib. hit(s) with all data for entry = 50016125
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165272BDBM50165272(8-(6-bromobenzo[d][1,3]dioxol-5-ylthio)-9-(pent-4-...)
Affinity DataEC50:  30nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20745BDBM20745(8-[(2-iodo-5-methoxyphenyl)sulfanyl]-9-(pent-4-yn-...)
Affinity DataEC50:  50nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165274BDBM50165274(8-(2-Bromo-5-methoxy-phenylsulfanyl)-9-pent-4-ynyl...)
Affinity DataEC50:  70nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165281BDBM50165281(8-(2-Chloro-3,4,5-trimethoxy-phenylsulfanyl)-2-flu...)
Affinity DataEC50:  120nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165264BDBM50165264(8-(2-Chloro-3,4,5-trimethoxy-phenylsulfanyl)-2-flu...)
Affinity DataEC50:  160nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165293BDBM50165293(8-(2-Chloro-3,4,5-trimethoxy-phenylsulfanyl)-9-pen...)
Affinity DataEC50:  180nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165279BDBM50165279(8-(2,5-Dimethoxy-phenylsulfanyl)-9-pent-4-ynyl-9H-...)
Affinity DataEC50:  190nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165276BDBM50165276(8-(2-Chloro-5-methoxy-phenylsulfanyl)-9-pent-4-yny...)
Affinity DataEC50:  200nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165272BDBM50165272(8-(6-bromobenzo[d][1,3]dioxol-5-ylthio)-9-(pent-4-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20745BDBM20745(8-[(2-iodo-5-methoxyphenyl)sulfanyl]-9-(pent-4-yn-...)
Affinity DataIC50: 810nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165303BDBM50165303(9-Butyl-8-(2-chloro-3,4,5-trimethoxy-phenylsulfany...)
Affinity DataEC50:  850nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165291BDBM50165291(8-(3-Methoxy-phenylsulfanyl)-9-pent-4-ynyl-9H-puri...)
Affinity DataEC50:  970nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165281BDBM50165281(8-(2-Chloro-3,4,5-trimethoxy-phenylsulfanyl)-2-flu...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165274BDBM50165274(8-(2-Bromo-5-methoxy-phenylsulfanyl)-9-pent-4-ynyl...)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15381BDBM15381(8-[(2-chloro-3,4,5-trimethoxyphenyl)methyl]-2-fluo...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165306BDBM50165306(8-(3-Methoxy-benzenesulfinyl)-9-pent-4-ynyl-9H-pur...)
Affinity DataEC50:  1.50E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165273BDBM50165273(2-Fluoro-9-pent-4-ynyl-8-(3,4,5-trimethoxy-phenyls...)
Affinity DataEC50:  1.50E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165299BDBM50165299(9-Pent-4-ynyl-8-(3,4,5-trimethoxy-phenylsulfanyl)-...)
Affinity DataEC50:  1.50E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165309BDBM50165309(8-(2,4-Dimethoxy-phenylsulfanyl)-9-pent-4-ynyl-9H-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165282BDBM50165282(8-(2,5-Dichloro-phenylsulfanyl)-9-pent-4-ynyl-9H-p...)
Affinity DataEC50:  2.10E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165267BDBM50165267(8-(2,6-Dichloro-3,4,5-trimethoxy-phenylsulfanyl)-9...)
Affinity DataEC50:  2.10E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165264BDBM50165264(8-(2-Chloro-3,4,5-trimethoxy-phenylsulfanyl)-2-flu...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165305BDBM50165305(9-(2-Isopropoxy-ethyl)-8-(3,4,5-trimethoxy-benzene...)
Affinity DataEC50:  2.30E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165310BDBM50165310(9-Butyl-8-(2-chloro-3,4,5-trimethoxy-phenylsulfany...)
Affinity DataEC50:  2.40E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165288BDBM50165288(2-Fluoro-9-(2-isopropoxy-ethyl)-8-(3,4,5-trimethox...)
Affinity DataEC50:  2.50E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165277BDBM50165277(1-[4-(6-Amino-9-pent-4-ynyl-9H-purin-8-ylsulfanyl)...)
Affinity DataEC50:  2.70E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165312BDBM50165312(9-(2-Isopropoxy-ethyl)-8-(3-methoxy-phenylsulfanyl...)
Affinity DataEC50:  2.80E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165292BDBM50165292(8-(2-Iodo-3,4,5-trimethoxy-phenylsulfanyl)-9-pent-...)
Affinity DataEC50:  3.10E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165318BDBM50165318(9-Butyl-8-(3,4,5-trimethoxy-phenylsulfanyl)-9H-pur...)
Affinity DataEC50:  3.10E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165279BDBM50165279(8-(2,5-Dimethoxy-phenylsulfanyl)-9-pent-4-ynyl-9H-...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165298BDBM50165298(8-(4-Chloro-phenylsulfanyl)-9-pent-4-ynyl-9H-purin...)
Affinity DataEC50:  3.40E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165301BDBM50165301(9-(2-Isopropoxy-ethyl)-8-(3,4,5-trimethoxy-phenyls...)
Affinity DataEC50:  3.40E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165276BDBM50165276(8-(2-Chloro-5-methoxy-phenylsulfanyl)-9-pent-4-yny...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165284BDBM50165284(9-(2-Isopropoxy-ethyl)-8-(3-methoxy-benzenesulfiny...)
Affinity DataEC50:  3.50E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165265BDBM50165265(8-(2-Chloro-5-trifluoromethyl-phenylsulfanyl)-9-pe...)
Affinity DataEC50:  3.70E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165271BDBM50165271(9-Butyl-8-(3-methoxy-phenylsulfanyl)-9H-purin-6-yl...)
Affinity DataEC50:  4.60E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165289BDBM50165289(9-Butyl-8-(3-methoxy-benzenesulfinyl)-9H-purin-6-y...)
Affinity DataEC50:  4.70E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165308BDBM50165308(9-Butyl-8-(2-chloro-3,4,5-trimethoxy-benzenesulfon...)
Affinity DataEC50:  4.80E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165313BDBM50165313(8-(2,4-Dichloro-5-methoxy-phenylsulfanyl)-9-(2-iso...)
Affinity DataEC50:  5.00E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165278BDBM50165278(9-Pent-4-ynyl-8-(2-trifluoromethoxy-phenylsulfanyl...)
Affinity DataEC50:  5.60E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165315BDBM50165315(9-Pent-4-ynyl-8-(2,4,5-trichloro-phenylsulfanyl)-9...)
Affinity DataEC50:  8.50E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165286BDBM50165286(8-(2,4-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-p...)
Affinity DataEC50:  8.60E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165293BDBM50165293(8-(2-Chloro-3,4,5-trimethoxy-phenylsulfanyl)-9-pen...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165276BDBM50165276(8-(2-Chloro-5-methoxy-phenylsulfanyl)-9-pent-4-yny...)
Affinity DataEC50:  9.60E+3nMAssay Description:Effective concentration of compound against heat shock protein HSP90 determined in normal lung cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165270BDBM50165270(2-Fluoro-9-pent-4-ynyl-8-(3,4,5-trimethoxy-benzyl)...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165319BDBM50165319(8-(3,5-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-p...)
Affinity DataEC50:  1.06E+4nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165308BDBM50165308(9-Butyl-8-(2-chloro-3,4,5-trimethoxy-benzenesulfon...)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165300BDBM50165300(8-(2,5-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-p...)
Affinity DataEC50:  1.34E+4nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165267BDBM50165267(8-(2,6-Dichloro-3,4,5-trimethoxy-phenylsulfanyl)-9...)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165274BDBM50165274(8-(2-Bromo-5-methoxy-phenylsulfanyl)-9-pent-4-ynyl...)
Affinity DataEC50:  1.44E+4nMAssay Description:Effective concentration of compound against heat shock protein HSP90 determined in normal brain cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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