Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50016540
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20330(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)
Affinity DataKi:  3.40nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20321(JYL1421 | CHEMBL388824 | 3-[(4-tert-butylphenyl)me...)
Affinity DataKi:  9.16nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170266(N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-3-...)
Affinity DataKi:  27.3nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170262(N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-3-...)
Affinity DataKi:  45.5nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20330(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)
Affinity DataKi:  50.4nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20321(JYL1421 | CHEMBL388824 | 3-[(4-tert-butylphenyl)me...)
Affinity DataKi:  53.5nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20315(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)
Affinity DataKi:  54nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20315(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)
Affinity DataKi:  63nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170253(N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-3-...)
Affinity DataKi:  119nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170262(N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-3-...)
Affinity DataKi:  144nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170251(2-Azido-ethanesulfonic acid {4-[3-(4-tert-butyl-be...)
Affinity DataKi:  145nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170252(N-{5-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-py...)
Affinity DataKi:  177nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170266(N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-3-...)
Affinity DataKi:  215nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170256(Ethenesulfonic acid {4-[3-(4-tert-butyl-benzyl)-th...)
Affinity DataKi:  231nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170251(2-Azido-ethanesulfonic acid {4-[3-(4-tert-butyl-be...)
Affinity DataKi:  231nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170264(N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-2-...)
Affinity DataKi:  400nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170253(N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-3-...)
Affinity DataKi:  440nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20284(N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...)
Affinity DataKi:  520nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170255(1-(4-tert-Butyl-benzyl)-3-(3-methylsulfanyl-benzyl...)
Affinity DataKi:  580nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170263(N-{4-[4-(tert-butyl)benzylamino(thioxo)methylamino...)
Affinity DataKi:  610nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50139640(N-4-Substituted-benzyl-N'-tert-butylbenzyl thioure...)
Affinity DataKi:  650nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170258(N-(4-{2-[3-(4-tert-Butyl-benzyl)-thioureido]-ethyl...)
Affinity DataKi:  699nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170267(N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-2-...)
Affinity DataKi:  750nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170257(1-(4-tert-Butyl-benzyl)-3-(3-methanesulfonyl-benzy...)
Affinity DataKi:  1.00E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170264(N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-2-...)
Affinity DataKi:  1.16E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20284(N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...)
Affinity DataKi:  1.30E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170263(N-{4-[4-(tert-butyl)benzylamino(thioxo)methylamino...)
Affinity DataKi:  1.30E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170265(N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-2-...)
Affinity DataKi:  3.60E+3nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170254(1-(4-tert-Butyl-benzyl)-3-(3-methanesulfinyl-benzy...)
Affinity DataKi:  3.60E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170258(N-(4-{2-[3-(4-tert-Butyl-benzyl)-thioureido]-ethyl...)
Affinity DataKi:  3.90E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170252(N-{5-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-py...)
Affinity DataKi:  4.10E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170260(N-{6-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-py...)
Affinity DataKi:  4.10E+3nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170268(2-Amino-ethanesulfonic acid {4-[3-(4-tert-butyl-be...)
Affinity DataKi:  4.64E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170259(N-{3-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-ph...)
Affinity DataKi:  6.00E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170261(N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-be...)
Affinity DataKi:  6.12E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170250(N-{4-[3-(4-tert-Butyl-benzyl)-thioureido]-phenyl}-...)
Affinity DataKi:  6.80E+3nMAssay Description:Antagonist activity for rat TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170265(N-{4-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-2-...)
Affinity DataKi:  8.07E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170250(N-{4-[3-(4-tert-Butyl-benzyl)-thioureido]-phenyl}-...)
Affinity DataKi:  9.56E+3nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50170260(N-{6-[3-(4-tert-Butyl-benzyl)-thioureidomethyl]-py...)
Affinity DataKi:  1.19E+4nMAssay Description:In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed