Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50016772
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173419BDBM50173419((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(5-(3-(trifl...)
Affinity DataKi:  2.70nMAssay Description:Inhibitory constant against Protease-activated receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173437BDBM50173437((3R,3aS,4S,4aR,8aS,9aR)-4-{(E)-2-[5-(3-Chloro-phen...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173419BDBM50173419((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(5-(3-(trifl...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173419BDBM50173419((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(5-(3-(trifl...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173433BDBM50173433((3R,3aS,4S,4aR,8aS,9aR)-4-{(E)-2-[5-(2-Methoxy-phe...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173417BDBM50173417((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-Ethyl-pyridin-...)
Affinity DataKi:  12nMAssay Description:Inhibitory constant against Protease-activated receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173409BDBM50173409((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-[(E)-2-(5-m-tol...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173410BDBM50173410((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-[(E)-2-(5-o-tol...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173418BDBM50173418((3R,3aS,4S,4aR,8aS,9aR)-4-{(E)-2-[5-(3-Isopropyl-p...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173451BDBM50173451((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(5-Benzyloxy-pyri...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173417BDBM50173417((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-Ethyl-pyridin-...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173438BDBM50173438((3R,3aS,4S,4aR,8aS,9aR)-4-{(E)-2-[5-(2-Fluoro-phen...)
Affinity DataIC50: 22nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173430BDBM50173430((3R,3aS,4S,4aR,8aS,9aR)-4-{(E)-2-[5-(3-Bromo-pheny...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173436BDBM50173436(3-{6-[(E)-2-((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-1-ox...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173447BDBM50173447((3R,3aS,4S,4aR,8aS,9aR)-4-{(E)-2-[5-(2-Chloro-phen...)
Affinity DataIC50: 26nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173421BDBM50173421((3R,3aS,4S,4aR,8aS,9aR,E)-3-methyl-4-(2-(5-phenylp...)
Affinity DataIC50: 27nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173446BDBM50173446((3R,3aS,4S,4aR,8aS,9aR)-4-{(E)-2-[5-(3-Methoxy-phe...)
Affinity DataIC50: 28nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173445BDBM50173445((3R,3aS,4S,4aR,8aS,9aR)-4-{(E)-2-[5-(3-Fluoro-phen...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173434BDBM50173434(2-{6-[(E)-2-((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-1-ox...)
Affinity DataIC50: 44nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173419BDBM50173419((3R,3aS,4S,4aR,8aS,9aR)-3-methyl-4-(2-(5-(3-(trifl...)
Affinity DataIC50: 44nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173450BDBM50173450((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-{(E)-2-[5-(2-tr...)
Affinity DataIC50: 46nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173417BDBM50173417((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-Ethyl-pyridin-...)
Affinity DataIC50: 85nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173417BDBM50173417((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-Ethyl-pyridin-...)
Affinity DataIC50: 85nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173431BDBM50173431(3-{6-[(E)-2-((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-1-ox...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173415BDBM50173415((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-Butyl-pyridin-...)
Affinity DataIC50: 143nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173424BDBM50173424((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-[(E)-2-(6-vinyl...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173426BDBM50173426((3R,3aS,4S,4aR,8aS,9aR)-4-{(E)-2-[5-(4-Methoxy-phe...)
Affinity DataIC50: 204nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173427BDBM50173427((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-Cyclopropyl-py...)
Affinity DataIC50: 210nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173449BDBM50173449((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-[(E)-2-(6-propy...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173425BDBM50173425((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-[(E)-2-(6-methy...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173412BDBM50173412((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-{(E)-2-[5-(4-tr...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173425BDBM50173425((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-[(E)-2-(6-methy...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173414BDBM50173414((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(5-Methoxy-pyridi...)
Affinity DataIC50: 325nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173420BDBM50173420((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-[(E)-2-(5-p-tol...)
Affinity DataIC50: 325nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173411BDBM50173411((3S,3aR,4R,4aS,8aR,9aS)-4-[(E)-2-(6-Ethyl-pyridin-...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173443BDBM50173443((3R,3aS,4S,4aR,8aS,9aR)-4-{(E)-2-[5-(4-Fluoro-phen...)
Affinity DataIC50: 467nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173422BDBM50173422((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-Isobutyl-pyrid...)
Affinity DataIC50: 550nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173439BDBM50173439((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-Isopropyl-pyri...)
Affinity DataIC50: 725nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173440BDBM50173440((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-Methoxymethyl-...)
Affinity DataIC50: 850nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173444BDBM50173444((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-Benzyl-pyridin...)
Affinity DataIC50: 900nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173432BDBM50173432((3R,3aS,4S,4aR,8aS,9aR)-4-{(E)-2-[5-(4-Chloro-phen...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173429BDBM50173429((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-[(E)-2-(5-methy...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173441BDBM50173441((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-[(E)-2-(6-methy...)
Affinity DataIC50: 1.25E+3nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173442BDBM50173442((3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[(E)-2-(6-methy...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173428BDBM50173428((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-Hydroxymethyl-...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173413BDBM50173413((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-[(E)-2-(4-methy...)
Affinity DataIC50: 2.10E+3nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173435BDBM50173435((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(6-Hexyl-pyridin-...)
Affinity DataIC50: 3.50E+3nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173448BDBM50173448((3R,3aS,4S,4aR,8aS,9aR)-4-[(E)-2-(5-Benzyl-pyridin...)
Affinity DataIC50: 3.68E+3nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173416BDBM50173416((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-((E)-2-pyridin-...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173423BDBM50173423((3R,3aS,4S,4aR,8aS,9aR)-3-Methyl-4-[(E)-2-(3-methy...)
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro inhibitory concentration against human protease activated receptor 1 using [3H]-haTRAP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed