Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50016817
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174074(4-(3-Methoxy-phenyl)-1-pentanoylamino-cyclohexanec...)
Affinity DataEC50:  2nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174078(Penta-Apc-DPhe-Arg-Trp-Gly-NH2 | 1-Pentanoylamino-...)
Affinity DataEC50:  2nMAssay Description:Effective concentration for cAMP accumulation mediated by human Melanocortin 4 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174081(1-Pentanoylamino-4-p-tolyl-cyclohexanecarboxylic a...)
Affinity DataEC50:  3nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174083(4-(4-Chloro-phenyl)-1-pentanoylamino-cyclohexaneca...)
Affinity DataEC50:  4nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174080(4-(4-Hydroxy-phenyl)-1-pentanoylamino-cyclohexanec...)
Affinity DataEC50:  5nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174077(4-(4-Isopropoxy-phenyl)-1-pentanoylamino-cyclohexa...)
Affinity DataEC50:  6nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174084(4-(4-Methoxy-phenyl)-1-pentanoylamino-cyclohexanec...)
Affinity DataEC50:  9nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataEC50:  10nMAssay Description:Effective concentration required for cAMP accumulation mediated by human Melanocortin 1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174073(4-(4-Ethoxy-phenyl)-1-pentanoylamino-cyclohexaneca...)
Affinity DataEC50:  13nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174078(Penta-Apc-DPhe-Arg-Trp-Gly-NH2 | 1-Pentanoylamino-...)
Affinity DataIC50: 13nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataEC50:  20nMAssay Description:Effective concentration for cAMP accumulation mediated by human Melanocortin 4 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174073(4-(4-Ethoxy-phenyl)-1-pentanoylamino-cyclohexaneca...)
Affinity DataIC50: 43nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174079(1-Pentanoylamino-4-phenyl-cyclohexanecarboxylic ac...)
Affinity DataEC50:  88nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174075(Penta-Apc-DPhe-Arg-Trp-NH2 | 1-Pentanoylamino-4-ph...)
Affinity DataEC50:  130nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 150nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174076(4-(3,5-Dipropyl-phenyl)-1-pentanoylamino-cyclohexa...)
Affinity DataEC50:  210nMAssay Description:Effective concentration required for cAMP accumulation mediated by human Melanocortin 1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174082(4-Phenyl-cyclohexanecarboxylic acid ((R)-1-{(S)-1-...)
Affinity DataEC50:  550nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 580nMAssay Description:Binding affinity towards human Melanocortin 1 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174074(4-(3-Methoxy-phenyl)-1-pentanoylamino-cyclohexanec...)
Affinity DataEC50:  690nMAssay Description:Effective concentration required for cAMP accumulation mediated by human Melanocortin 1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121890(2-Pentanoylamino-1,2,3,4-tetrahydro-naphthalene-2-...)
Affinity DataEC50:  830nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121890(2-Pentanoylamino-1,2,3,4-tetrahydro-naphthalene-2-...)
Affinity DataEC50:  830nMAssay Description:Effective concentration required for cAMP accumulation mediated by human Melanocortin 1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174075(Penta-Apc-DPhe-Arg-Trp-NH2 | 1-Pentanoylamino-4-ph...)
Affinity DataEC50:  1.30E+3nMAssay Description:Effective concentration required for cAMP accumulation mediated by human Melanocortin 1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174080(4-(4-Hydroxy-phenyl)-1-pentanoylamino-cyclohexanec...)
Affinity DataEC50:  1.30E+3nMAssay Description:Effective concentration required for cAMP accumulation mediated by human Melanocortin 1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174079(1-Pentanoylamino-4-phenyl-cyclohexanecarboxylic ac...)
Affinity DataEC50:  1.30E+3nMAssay Description:Effective concentration required for cAMP accumulation mediated by human Melanocortin 1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity towards human Melanocortin 3 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121892(2-Butyrylamino-1,2,3,4-tetrahydro-naphthalene-2-ca...)
Affinity DataEC50:  4.40E+3nMAssay Description:Effective concentration required for cAMP accumulation mediated by human Melanocortin 1 receptor in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121892(2-Butyrylamino-1,2,3,4-tetrahydro-naphthalene-2-ca...)
Affinity DataEC50:  4.40E+3nMAssay Description:Binding affinity towards human Melanocortin 4 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174073(4-(4-Ethoxy-phenyl)-1-pentanoylamino-cyclohexaneca...)
Affinity DataIC50: 4.70E+3nMAssay Description:Binding affinity towards human Melanocortin 1 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50174078(Penta-Apc-DPhe-Arg-Trp-Gly-NH2 | 1-Pentanoylamino-...)
Affinity DataIC50: 7.10E+3nMAssay Description:Binding affinity towards human Melanocortin 1 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50121885((S)-2-{(R)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Affinity DataIC50: 1.30E+4nMAssay Description:Binding affinity towards human Melanocortin 5 receptor using radiolabeled NDP-MSH displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed