Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 50016927
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175387((R)-2-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)pr...)
Affinity DataIC50:  30nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50161093((R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthale...)
Affinity DataIC50:  50nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175382((S)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthale...)
Affinity DataIC50:  50nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175375((S)-2-(3-(1-(benzo[b]thiophen-2-yl)-2-methylpropan...)
Affinity DataIC50:  60nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175360((S)-2-(3-(1-(1H-indol-2-yl)-2-methylpropan-2-ylami...)
Affinity DataIC50:  100nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175384(2-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen...)
Affinity DataIC50:  140nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175365(2-fluoro-6-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(n...)
Affinity DataIC50:  140nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175380((R)-1-((R)-1-(3-nitrobenzyl)pyrrolidin-2-yl)-2-(2-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175354((R)-1-((R)-1-(2-nitrobenzyl)pyrrolidin-2-yl)-2-(2-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175371(3-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen...)
Affinity DataIC50:  190nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175377(2-chloro-6-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(n...)
Affinity DataIC50:  240nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175362(4-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen...)
Affinity DataIC50:  250nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175374((R)-2-chloro-6-(2-hydroxy-3-(methyl(2-methyl-1-(na...)
Affinity DataIC50:  270nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175363(3-(((R)-2-((R)-2-(1-(benzo[b]thiophen-2-yl)-2-meth...)
Affinity DataIC50:  270nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175386(2-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen...)
Affinity DataIC50:  340nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175378((R)-1-((R)-1-(2,3-difluorobenzyl)pyrrolidin-2-yl)-...)
Affinity DataIC50:  360nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175370(3-(((R)-2-((R)-2-(1-(1H-indol-2-yl)-2-methylpropan...)
Affinity DataIC50:  440nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50161093((R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthale...)
Affinity DataIC50:  530nMAssay Description:Inhibition of extracellular calcium-induced inositol triphosphate generation in rat MTC cells expressing calcium-sensing receptorMore data for this Ligand-Target Pair
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175357((R)-2-chloro-6-(3-(1-(4-fluorophenyl)-2-methylprop...)
Affinity DataIC50:  600nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175381((R)-1-((R)-1-(3-fluorobenzyl)pyrrolidin-2-yl)-2-(2...)
Affinity DataIC50:  750nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175368((R)-1-((R)-1-(4-nitrobenzyl)pyrrolidin-2-yl)-2-(2-...)
Affinity DataIC50:  790nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175352(2-chloro-6-(3-(2-methyl-1-(naphthalen-2-yl)propan-...)
Affinity DataIC50:  880nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175353(2-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen...)
Affinity DataIC50:  970nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175358(3-(((R)-2-((R)-2-(1-(benzo[b]thiophen-3-yl)-2-meth...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175355(3-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175372((R)-1-((R)-1-(3-methoxybenzyl)pyrrolidin-2-yl)-2-(...)
Affinity DataIC50:  1.19E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175379(2-(((R)-2-((S)-1-hydroxy-2-(2-methyl-1-(naphthalen...)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175361(3-(((R)-2-((R)-2-(1-(benzo[d]thiazol-2-yl)-2-methy...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175388((S)-1-(3-methoxyphenoxy)-3-(1-(4-methoxyphenyl)-2-...)
Affinity DataIC50:  1.39E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175359(2-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen...)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175376((R)-1-((R)-1-(3-bromobenzyl)pyrrolidin-2-yl)-2-(2-...)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175371(3-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of extracellular calcium-induced inositol triphosphate generation in rat MTC cells expressing calcium-sensing receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175391((R)-1-((R)-1-Biphenyl-3-ylmethyl-pyrrolidin-2-yl)-...)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Rattus norvegicus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175365(2-fluoro-6-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(n...)
Affinity DataIC50:  2.56E+3nMAssay Description:Inhibition of extracellular calcium-induced inositol triphosphate generation in rat MTC cells expressing calcium-sensing receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175364(3-(((R)-2-((R)-1-hydroxy-2-(1-(4-methoxyphenyl)-2-...)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175390(3-(((R)-2-((R)-2-(1-(1H-benzo[d]imidazol-2-yl)-2-m...)
Affinity DataIC50:  2.84E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175383((R)-1-(1-(4-fluorophenyl)-2-methylpropan-2-ylamino...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175366((R)-2-chloro-6-(2-hydroxy-3-(2-(naphthalen-2-yl)et...)
Affinity DataIC50:  3.86E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175385((R)-2-chloro-6-(2-hydroxy-3-(naphthalen-2-ylamino)...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175367((R)-1-(2,3-dichlorophenylthio)-3-(1-(4-fluoropheny...)
Affinity DataIC50:  6.18E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175373(3-(((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen...)
Affinity DataIC50:  6.84E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175369(3-((R)-2-((R)-1-hydroxy-2-(2-methyl-1-(naphthalen-...)
Affinity DataIC50:  8.43E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175389((S)-1-(2-methyl-1-phenylpropan-2-ylamino)-3-(2-(me...)
Affinity DataIC50:  9.43E+3nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50175356(1-(1-(4-methoxyphenyl)-2-methylpropan-2-ylamino)-3...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed