Compile Data Set for Download or QSAR
Report error Found 101 Enz. Inhib. hit(s) with all data for entry = 50017215
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179135((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50: 0.620nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179134((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 0.800nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179142((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50: 0.910nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119368((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50: 1.20nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179141((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  1.30nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179141((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 1.30nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119368((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50:  2.10nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179143((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 2.10nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179134((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  2.40nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179137((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 4nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179136((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 4.30nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179140((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 4.5nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179139((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179133((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 4.80nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179142((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50:  5.30nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179143((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  5.60nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179137((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  5.80nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179135((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50:  5.80nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179139((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50:  6.10nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179132((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50: 7.90nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179138(ethyl (1-((R)-3-(4-chlorophenyl)-2-((R)-1,2,3,4-te...)
Affinity DataIC50: 8.10nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179140((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  8.60nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179138(ethyl (1-((R)-3-(4-chlorophenyl)-2-((R)-1,2,3,4-te...)
Affinity DataEC50:  14nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179132((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50:  15nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179136((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  16nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179133((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  16nMAssay Description:Activity against human MC4R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179134((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 80nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179141((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 110nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179133((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 150nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179136((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 160nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179142((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50: 170nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179139((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50: 170nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179137((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 180nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179135((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50: 190nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179143((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179141((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 210nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179132((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50: 210nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179140((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 220nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179134((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 230nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179137((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  280nMAssay Description:Activity against human MC5R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179142((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50: 310nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50119368((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50: 326nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179134((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  340nMAssay Description:Activity against human MC5R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179141((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  370nMAssay Description:Activity against human MC3R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179143((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataIC50: 380nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179140((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  400nMAssay Description:Activity against human MC5R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179141((R)-N-((R)-3-(4-chlorophenyl)-1-(4-cyclohexyl-4-((...)
Affinity DataEC50:  400nMAssay Description:Activity against human MC5R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179132((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataIC50: 400nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3R expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179135((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50:  450nMAssay Description:Activity against human MC3R by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50179135((R)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataEC50:  460nMAssay Description:Activity against human MC1BR by cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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