Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 2306
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 19nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 20nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 28nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM19158((3S,9S,14aR)-9-benzyl-3-(7-bromo-6-oxoheptyl)-6,6-...)
Affinity DataIC50: 59.5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM19162((3S,9S,14aR)-9-benzyl-3-(7-hydroxy-6-oxoheptyl)-6,...)
Affinity DataIC50: 60.4nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM19158((3S,9S,14aR)-9-benzyl-3-(7-bromo-6-oxoheptyl)-6,6-...)
Affinity DataIC50: 61.9nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM19162((3S,9S,14aR)-9-benzyl-3-(7-hydroxy-6-oxoheptyl)-6,...)
Affinity DataIC50: 223nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM19159((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-(6-oxoheptyl)...)
Affinity DataIC50: 290nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM19158((3S,9S,14aR)-9-benzyl-3-(7-bromo-6-oxoheptyl)-6,6-...)
Affinity DataIC50: 621nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM19162((3S,9S,14aR)-9-benzyl-3-(7-hydroxy-6-oxoheptyl)-6,...)
Affinity DataIC50: 887nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM19159((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-(6-oxoheptyl)...)
Affinity DataIC50: 1.08E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM19161(6-[(3S,9S,14aR)-9-benzyl-6,6-dimethyl-1,4,7,10-tet...)
Affinity DataIC50: 1.29E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM19159((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-(6-oxoheptyl)...)
Affinity DataIC50: 3.70E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM19157((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-[5-(oxiran-2-...)
Affinity DataIC50: 4.05E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM19161(6-[(3S,9S,14aR)-9-benzyl-6,6-dimethyl-1,4,7,10-tet...)
Affinity DataIC50: 4.33E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM19157((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-[5-(oxiran-2-...)
Affinity DataIC50: 4.69E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM19161(6-[(3S,9S,14aR)-9-benzyl-6,6-dimethyl-1,4,7,10-tet...)
Affinity DataIC50: 1.41E+4nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM19160((3S,9S,14aR)-9-benzyl-3-(6,7-dihydroxyheptyl)-6,6-...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM19160((3S,9S,14aR)-9-benzyl-3-(6,7-dihydroxyheptyl)-6,6-...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM19156((3S,9S,14aR)-9-benzyl-3-(hept-6-en-1-yl)-6,6-dimet...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Kyushu Institute of Technology

LigandPNGBDBM19160((3S,9S,14aR)-9-benzyl-3-(6,7-dihydroxyheptyl)-6,6-...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM19156((3S,9S,14aR)-9-benzyl-3-(hept-6-en-1-yl)-6,6-dimet...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Kyushu Institute of Technology

LigandPNGBDBM19156((3S,9S,14aR)-9-benzyl-3-(hept-6-en-1-yl)-6,6-dimet...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Kyushu Institute of Technology

LigandPNGBDBM19157((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-[5-(oxiran-2-...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2007
Entry Details Article
PubMed